UNCARINE D

UNCARINE D Structure
CAS No.
4697-68-1
Chemical Name:
UNCARINE D
Synonyms
Nsc113094;Uncarin D;UNCARINE D;SPECIOPHYLLINE;Speciophylline (Uncarine D);(3β,7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aR,10'aS)-
CBNumber:
CB1202115
Molecular Formula:
C21H24N2O4
Molecular Weight:
368.43
MOL File:
4697-68-1.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:39

UNCARINE D Properties

Melting point 183~184℃
Boiling point 555.2±50.0 °C(Predicted)
Density 1.33
pka 13.56±0.60(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501

UNCARINE D Chemical Properties,Uses,Production

Description

One of the alkaloids isolated from the leaves of Mitragyna speciosa, the structure of the base has been determined from the NMR spectrum which demonstrates that the alkaloid has a cis DIE ring junction and a conformation such that the oxindole ring deshields the ester methoxyl group.

Uses

Uncarine D is a compound extracted from Uncaria tomentosa leaves. The compounds extracted from these leaves have exhibited immunomodulating, antiinflammatory and anti-cancer activity, attributed to the presence of tetra/pentacyclic oxindole alkaloids.

References

Beckett et al., Sci. Pharm., Froc., 25th (1965)

UNCARINE D Preparation Products And Raw materials

Raw materials

Preparation Products

UNCARINE D Suppliers

Global( 15)Suppliers
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Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Shaanxi Pioneer Biotech Co., Ltd . +8613259417953 China 3000 58 Inquiry
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 China 7892 56 Inquiry
JinJin Le Chemical Co., Ltd 10106090 China 9986 58 Inquiry
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 China 12664 58 Inquiry
SHANGHAI ZZBIO CO., LTD. 19921389125 19921389125 China 12065 58 Inquiry
ChromaDex 949 419 0288 United States 2501 76 Inquiry
Sequoia Research Products Ltd. 44 7802 291086 United Kingdom 3115 69 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
2A PharmaChem USA (630) 737-0988 United States 6148 39 Inquiry
(3β,7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester Nsc113094 Speciophylline (Uncarine D) Uncarin D SPECIOPHYLLINE UNCARINE D Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aR,10'aS)- 4697-68-1