Chinese english Japanese Germany Korea

SU 6656

SU 6656 Structure
CAS No.
330161-87-0
Chemical Name:
SU 6656
Synonyms
CS-1672;SU 6656;SU-6656;SU6656 - CAS 330161-87-0 - Calbiochem;N,N-diMethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)Methyl)indoline-5-sulfonaMide;N,N-Dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indoline-5-sulfonamide;2,3-dihydro-n,n-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1h-indol-2-yl)methylene]-1h-indole-5-sulfonamide;1H-Indole-5-sulfonamide, 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-;PTK2 protein tyrosine kinase 2,Focal adhesion kinase,FAK,Akt,SU-6656,PTK2,Inhibitor,Protein kinase B,SU 6656,SU6656,Src,PKB,inhibit
CBNumber:
CB0504775
Molecular Formula:
C19H21N3O3S
Molecular Weight:
371.45
MOL File:
330161-87-0.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

SU 6656 Properties

Density 1.378±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: 12 mg/mL orange solution
pka 11.87±0.20(Predicted)
form powder
color orange-brown
InChIKey LOGJQOUIVKBFGH-YBEGLDIGSA-N

SAFETY

Risk and Safety Statements

WGK Germany  3

SU 6656 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S9692 SU 6656 ≥98% (HPLC) 330161-87-0 5MG ₹16486.48 2022-06-14 Buy
Sigma-Aldrich(India) S9692 SU 6656 ≥98% (HPLC) 330161-87-0 25MG ₹58920.48 2022-06-14 Buy
Sigma-Aldrich(India) 572635 SU6656 - CAS 330161-87-0 - Calbiochem A potent, cell-permeable, reversible, and ATP-competitive Src family kinase inhibitor. 330161-87-0 1MG ₹23979.99 2022-06-14 Buy
Product number Packaging Price Buy
S9692 5MG ₹16486.48 Buy
S9692 25MG ₹58920.48 Buy
572635 1MG ₹23979.99 Buy

SU 6656 Chemical Properties,Uses,Production

Description

The Src family of proto-oncogenic kinases include nine mammalian non-receptor tyrosine kinases that are involved in intracellular signaling and are often relevant to carcinogenesis. SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). It weakly inhibits some other kinases when used at >10 μM. SU6656 has been used to study the role of Src kinases in cell growth and development in diverse processes, including nervous system development, fibrosis, and cancer.

Uses

SU 6656 is a small molecule selective inhibitor of the Src kinase family and induces caspase-independant cancer cell death.

General Description

A potent, cell-permeable, reversible, and ATP-competitive inhibitor of Src-family protein tyrosine kinases. Inhibits Src (IC50 = 280 nM) as well as closely related kinases Fyn (IC50 = 170 nM), Yes (IC50 = 20 nM) and Lyn (IC50 = 130 nM). The inhibition is competitive with respect to ATP. Has only a trivial effect on Lck (IC50 = 6.88 μM). Does not affect the activity of PDGF-β receptor kinase (IC50 ≥10 μM) and IGF-1 receptor kinase (IC50 ≥20 μM).

SU 6656 Preparation Products And Raw materials

Raw materials

Preparation Products

SU 6656 Suppliers

Global( 89)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 4692 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
LEAP CHEM CO., LTD. 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Aladdin Scientific 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 58

SU 6656 Spectrum

SU 6656(330161-87-0)1HNMR

330161-87-0(SU 6656)Related Search:

SU 5416 5-CHLORO-3-[(3,5-DIMETHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE SU 9516 SU 6656
N,N-diMethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)Methyl)indoline-5-sulfonaMide 2,3-dihydro-n,n-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1h-indol-2-yl)methylene]-1h-indole-5-sulfonamide SU6656 - CAS 330161-87-0 - Calbiochem SU 6656;SU-6656 CS-1672 1H-Indole-5-sulfonamide, 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]- PTK2 protein tyrosine kinase 2,Focal adhesion kinase,FAK,Akt,SU-6656,PTK2,Inhibitor,Protein kinase B,SU 6656,SU6656,Src,PKB,inhibit N,N-Dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indoline-5-sulfonamide 330161-87-0