SU 5416

CAS No.: 204005-46-9

Chemical Name:: SU 5416

Synonyms: 17022;SU54161;SeMaxinib;(Z)-3-((3;Sugen 5416;SU5416 /SU-5416;SU 5416 semaxanib;SEMAXINIB(SU 5416);SU 5416 (SeMaxinib);VEGFR2 Kinase Inhibitor III

CBNumber:: CB8504771

Molecular Formula:: C15H14N2O

Molecular Weight:: 238.28

MOL File:: 204005-46-9.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

SU 5416 Properties

Melting point	226-228 °C
Boiling point	481.4±45.0 °C(Predicted)
Density	1.256±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	H₂O: insoluble
pka	12.59±0.20(Predicted)
form	Yellow orange solid
color	yellow to yellow orange

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H335-H319-H315

Precautionary statements

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

HS Code

29339900

NFPA 704

	0
2		0

SU 5416 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	S8442	SU 5416 ≥98% (HPLC)	204005-46-9	5MG	₹13163.2	2022-06-14	Buy
Sigma-Aldrich(India)	S8442	SU 5416 ≥98% (HPLC)	204005-46-9	25MG	₹52663.63	2022-06-14	Buy

Product number	Packaging	Price	Buy
S8442	5MG	₹13163.2	Buy
S8442	25MG	₹52663.63	Buy

SU 5416 Chemical Properties,Uses,Production

Biological Activity

Inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET. Displays no activity against EGFR, HER2, IGF1R and PDGFR. Inhibits tumor vascularization and growth of multiple tumor types.

Biochem/physiol Actions

SU 516 inhibits the activity of neuronal nitric oxide synthase and protects the neuronal cells from nitric oxide-mediated neurotoxicity.1 It also acts an agonist of aryl hydrocarbon receptor and is an effective clinical agent for treating autoimmune diseases and transplant rejection.2

SU 5416 Preparation Products And Raw materials

Raw materials

Preparation Products

SU 5416 Suppliers

Global( 159)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29897	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	China	5738	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry
Labnetwork lnc.	+86-27-50766799 +8618062016861	China	19994	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Nextpeptide Inc	58
Labnetwork lnc.	58

SU 5416 Spectrum

SU 5416(204005-46-9)¹HNMR

204005-46-9(SU 5416)Related Search:

SU 6656 N,N-Dimethylaniline 5,5-Dimethylhydantoin 5-CHLORO-3-[(3,5-DIMETHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE SU5402

N-Desethyl Sunitinib SU 9516 SU 5205 SU4312 VEGFR2 Kinase Inhibitor I

SU5208 SU 11274 Sunitinib Malate Sunitinib PHA-665752

SU 5416 N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide SUNITINIB-D10

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H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro- SeMaxinib SU 5416 (SeMaxinib) SU5416 /SU-5416 (Z)-3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one 3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one 3-[(3,5-diMethyl-1H-pyrrol-2-yl)Methylidene]-1H-indol-2-one SEMAXINIB(SU 5416) 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one VEGFR2 Kinase Inhibitor III 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-on 17022 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one (3Z)-3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one SEMAXINIB; SU-5416; SU 5416 (E)-3-((3,5-DIMETHYL-1H-PYRROL-2-YL)METHYLENE)INDOLIN-2-ONE VEGFR2 Kinase Inhibitor III - CAS 204005-46-9 - Calbiochem 5-Dimethyl-1H-pyrrol-2-yl)met hylene)indolin-2-one (Z)-3-((3 SU5416; SU-5416; SU 5416; SUGEN 5416; SEMOXIND; SEMAXANIB Sugen 5416 SU 5416, 98%, a VEGFR2/Flk1 inhibitor SU 5416 semaxanib SU54161 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro- 204005-46-9 Angiogenesis and Metastasis Inhibitors