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2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Structure
CAS No.
60762-57-4
Chemical Name:
2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE
Synonyms
Pirlindol;Pyrazidol;Pirlindole;Pirlindolum;Unii-V39yph45fz;PIRLINDOLE MESYLATE;Pirlindole free base;Ombitasvir Impurity 6;Pirlindolum [inn-latin];16154-78-2 (Hydrochloride)
CBNumber:
CB0671512
Molecular Formula:
C15H18N2
Molecular Weight:
226.32
MOL File:
60762-57-4.mol
Modify Date:
2025/3/29 7:52:27
Request For Quotation

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Properties

storage temp. Store at RT
solubility DMF: 1 mg/ml; DMSO: 5 mg/ml
form A crystalline solid
color Off-white to light yellow

SAFETY

Risk and Safety Statements

HazardClass  IRRITANT

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Chemical Properties,Uses,Production

Description

Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor (IC50s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively). It is selective for MAO-A over MAO-B (Kis = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively). In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC50 value of 7.7 μM independent of MAO-A activity.

Uses

Antidepressive;Monoamine oxidase inhibitor

Biological Activity

A highly selective reversible inhibitor of monoamine oxidase type A.

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Suppliers

Global( 46)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32159 58 Inquiry
Aladdin Scientific United States 52924 58 Inquiry
TargetMol Chemicals Inc. +8613564774135 United States 19881 58 Inquiry
Shaanxi Dideu New Materials Co. Ltd +86-18192503167 +86-18192503167 China 3512 58 Inquiry
DAYANG CHEM (HANGZHOU) CO.,LTD +8617705817739 China 53881 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131957 58 Inquiry
Matrix Scientific 803 788-9494 All other calls United States 6632 80 Inquiry
Tcichem, Inc. 13918644899 China 1787 55 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6650 58 Inquiry
Combi-Blocks Inc. 858 635 8950 United States 6618 69 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
TargetMol Chemicals Inc. 58
Shaanxi Dideu New Materials Co. Ltd 58
DAYANG CHEM (HANGZHOU) CO.,LTD 58
Amadis Chemical Company Limited 58
Matrix Scientific 80
Tcichem, Inc. 55
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Combi-Blocks Inc. 69

60762-57-4(2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE)Related Search:

1,10-Trimethylene-2-butyl-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-a)in dole hydrochloride 1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-3-prop yl-, hydrochloride 10-CYCLOHEXYL-1,2,3,3A,4,5-HEXAHYDRO-6H-PYRAZINO[1,2,3-L,M]CARBAZOLE 3-BENZYL-2,3,3A,4,5,6-HEXAHYDRO-1H-PYRAZINO[3,2,1-JK]CARBAZOLE-8-CARBALDEHYDE 2-CHLORO-1-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO[3,2,1-JK]CARBAZOL-3-YL)-ETHANONE
2,3,3A,4,5,6-HEXAHYDRO-8-CYCLOHEXYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE 3-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO-[3,2,1-JK]CARBAZOL-3-YL)PROPIONIC ACID 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE 8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-3H-PYRAZINO[3,2,1-JK]CARBAZOLE-3-CARBALDEHYDE
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PIRLINDOLE MESYLATE 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole 16154-78-2 (Hydrochloride) Pirlindol Pirlindol [inn-spanish, french] Pirlindolum Pirlindolum [inn-latin] Unii-V39yph45fz Pirlindole 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino-[3,2,1-jk]carbazole methanesulfonate 1H-Pyrazino[3,2,1-jk]carbazole,2,3,3a,4,5,6-hexahydro-8-methyl- Pirlindole free base Pyrazidol Ombitasvir Impurity 6 60762-57-4 C15H18N2CH3SO3H Monoamine Oxidase