ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Epigenetics >HDAC inhibitors >M344
M344
- CAS No.
- 251456-60-7
- Chemical Name:
- M344
- Synonyms
- M344;CS-661;MS 344;M344 (D 237);MS 344, D237;M344 USP/EP/BP;M 344 (enzyme inhibitor);HISTONE DEACETYLASE INHIBITOR III;Histone Deacetylase Inhibitor III(M344);N-HYDROXY-7-(4-DIMETHYLAMINOBENZOYL)AMINOHEPTANAMIDE
- CBNumber:
- CB0673778
- Molecular Formula:
- C16H25N3O3
- Molecular Weight:
- 307.39
- MOL File:
- 251456-60-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:37
| Melting point | 161℃ |
|---|---|
| Density | 1.137±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble10mg/mL, clear |
| pka | 9.48±0.20(Predicted) |
| form | White solid |
| color | white to beige |
| Sensitive | Light Sensitive |
| CAS DataBase Reference | 251456-60-7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P302+P352-P305+P351+P338-P321-P405-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2928.00.2500 | |||||||||
| NFPA 704 |
|
M344 price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M5820 | M344 ≥98% (HPLC), powder | 251456-60-7 | 1MG | ₹19658.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M5820 | M344 ≥98% (HPLC), powder | 251456-60-7 | 5MG | ₹77885.88 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 382149 | Histone Deacetylase Inhibitor III The Histone Deacetylase Inhibitor III, also referenced under CAS 251456-60-7, controls the biological activity of Histone Deacetylase. This small mole | 251456-60-7 | 1MG | ₹17860 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D4188 | 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide | 251456-60-7 | 20MG | ₹5600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D4188 | 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide | 251456-60-7 | 100MG | ₹19600 | 2022-05-26 | Buy |
M344 Chemical Properties,Uses,Production
Uses
Histone deacetylase inhibitor III. A cell-permeable amide analog of Trichostatin A that potently inhibits HDACs.
General Description
A cell-permeable amide analog of Trichostatin A (Cat. No. 647925) that potently inhibits histone deacetylases (IC50 = 40 nM for rat liver HDAC and IC50 = 100 nM for maize HD). Induces differentiation and inhibits proliferation (~2 μM) of murine erythroleukemia cells.
Biological Activity
Histone deacetylase inhibitor (IC 50 = 100 nM). Induces terminal cell differentiation and causes an increase in hyperacetylated histone H4. Antiproliferative agent; suppresses the growth of human endometrial and ovarian cancer cells by inducing cell cycle arrest and apoptosis.
M344 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 130)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9626 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
251456-60-7(M344)Related Search:
M344
HISTONE DEACETYLASE INHIBITOR III
4-DIMETHYLAMINO-N-(6-HYDROXYCARBAMOYLHEXYL)-BENZAMIDE
N-HYDROXY-7-(4-DIMETHYLAMINOBENZOYL)AMINOHEPTANAMIDE
4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide, MS 344, D237, N-Hydroxy-7-(4-dimethylaminobenzoyl)-aminoheptanamide
4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide
MS 344
M 344 (enzyme inhibitor)
4-(Diethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
MS 344, D237
M344 (D 237)
4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide>
Benzamide, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-
M344 USP/EP/BP
HISTONE DEACETYLASE INHIBITOR III;D237;D 237;D-237;M-344;M344
CS-661
Histone Deacetylase Inhibitor III(M344)
M344 HDAC inhibitor M-344 Histone Deacetylase Inhibitor III
251456-60-7
51456-60-7
DNA-RNA Transcription Regulators
Gene Regulation and Expression
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Amines
Aromatics
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals
Inhibitor
Apoptosis Inducers