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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Epigenetics >HDAC inhibitors >M344

M344

M344 Structure
  • ₹5600 - ₹77885.88
  • Product name: M344
  • CAS: 251456-60-7
  • MF: C16H25N3O3
  • MW: 307.39
  • EINECS:
  • MDL Number:MFCD03453554
  • Synonyms:M344;HISTONE DEACETYLASE INHIBITOR III;4-DIMETHYLAMINO-N-(6-HYDROXYCARBAMOYLHEXYL)-BENZAMIDE;N-HYDROXY-7-(4-DIMETHYLAMINOBENZOYL)AMINOHEPTANAMIDE;4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide, MS 344, D237, N-Hydroxy-7-(4-dimethylaminobenzoyl)-aminoheptanamide;4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide;MS 344;M 344 (enzyme inhibitor)
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 20MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberD4188
  • Product description4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
  • Packaging20MG
  • Price₹5600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4188
  • Product description4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
  • Packaging100MG
  • Price₹19600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM5820
  • Product descriptionM344 ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹77885.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM5820
  • Product descriptionM344 ≥98% (HPLC), powder
  • Packaging1MG
  • Price₹19658.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number382149
  • Product descriptionHistone Deacetylase Inhibitor III The Histone Deacetylase Inhibitor III, also referenced under CAS 251456-60-7, controls the biological activity of Histone Deacetylase. This small mole
  • Packaging1MG
  • Price₹17860
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4188 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 20MG ₹5600 2022-05-26 Buy
TCI Chemicals (India) D4188 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 100MG ₹19600 2022-05-26 Buy
Sigma-Aldrich(India) M5820 M344 ≥98% (HPLC), powder 5MG ₹77885.88 2022-06-14 Buy
Sigma-Aldrich(India) M5820 M344 ≥98% (HPLC), powder 1MG ₹19658.2 2022-06-14 Buy
Sigma-Aldrich(India) 382149 Histone Deacetylase Inhibitor III The Histone Deacetylase Inhibitor III, also referenced under CAS 251456-60-7, controls the biological activity of Histone Deacetylase. This small mole 1MG ₹17860 2022-06-14 Buy

Properties

Melting point :161℃
Density :1.137±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :9.48±0.20(Predicted)
form :White solid
color :white to beige
Sensitive :Light Sensitive
CAS DataBase Reference :251456-60-7

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1. M 344 enhances the sensitivity of human squamous carcinoma cells to radiation and promotes cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells (ED50 = 2.3 μM).

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Suppliers and manufacturers

career henan chemical co
M344
₹1.00 /1g
M344 CAS:51456-60-7
CLEARSYNTH LABS LTD. A.J Chemicals TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
TargetMol Chemicals Inc.
Dideu Industries Group Limited
Finetech Industry Limited
Zhejiang J&C Biological Technology Co.,Limited