CGP 55845

CAS No.: 149184-22-5

Chemical Name:: CGP 55845

Synonyms: CGP 55845;CGP 55845 hydrochlor;CGP 55845 hydrochloride;benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid;(2S)-3-[[(1S)-1-(3,4-DICHLOROPHENYL)ETHYL]AMINO-2-HYDROXYPROPYL](PHENYLMETHYL)PHOSPHINIC ACID;(2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinicacidhydrochloride

CBNumber:: CB0718390

Molecular Formula:: C18H23Cl3NO3P

Molecular Weight:: 438.71

MOL File:: 149184-22-5.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

CGP 55845 Properties

storage temp.	room temp
solubility	DMSO: soluble5mg/mL, clear (warmed)
form	powder
color	white to beige

SAFETY

Risk and Safety Statements

WGK Germany	3
RTECS	SZ4680000

CGP 55845 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SML0594	CGP 55845 hydrochloride ≥98% (HPLC)	149184-22-5	5MG	₹13726.1	2022-06-14	Buy
Sigma-Aldrich(India)	SML0594	CGP 55845 hydrochloride ≥98% (HPLC)	149184-22-5	25MG	₹54806.98	2022-06-14	Buy

Product number	Packaging	Price	Buy
SML0594	5MG	₹13726.1	Buy
SML0594	25MG	₹54806.98	Buy

CGP 55845 Chemical Properties,Uses,Production

Uses

CGP is a potent, selectie GABAB receptor antagonist.

Biological Activity

Potent, selective GABA B receptor antagonist (IC 50 = 5 nM) that prevents agonist binding (pK i = 8.35) and inhibits GABA and glutamate release (pEC 50 values are 8.08 and 7.85 respectively). Inhibits GABA B responses to baclofen (IC 50 = 130 nM in an isoproterenol assay) and potentiates the hypoglycemic response to glucose in vitro .

Biochem/physiol Actions

CGP 55845 is a potent selective GABA-B receptor antagonist with an IC50 of 5 nM.

CGP 55845 Preparation Products And Raw materials

Raw materials

Preparation Products

CGP 55845 Suppliers

Global( 24)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	China	8141	58	Inquiry
Shanghai Universal Biotech Co.,Ltd	18768175414	China	24998	58	Inquiry
Xi'an Qiyue Biotechnology Co., Ltd.	400-400-6966-012-012 17778955912	China	2535	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	24017	58	Inquiry
BOC Sciences		USA	0	65	Inquiry
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	China	4398	58	Inquiry
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	China	5595	58	Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	China	15848	69	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Aladdin Scientific	58
MedBioPharmaceutical Technology Inc	58
Shanghai Universal Biotech Co.,Ltd	58
Xi'an Qiyue Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58
BOC Sciences	65
Nantong QuanYi Biotechnology Co., Ltd	58
Nanjing Tengyi Biotechnology Co., Ltd	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69

149184-22-5(CGP 55845)Related Search:

Hypophosphorous acid CGP 55845A 1-(3,4-DICHLORO-PHENYL)-ETHYLAMINE 2-(3,4-DICHLORO-BENZYLAMINO)-ETHANOL Benzenemethanamine, 3,4-dichloro-a-methyl-, (S)-

(S)-1-(3-Chlorophenyl)ethylamine (S)-1-(4-Chlorophenyl)ethylamine 3-AMINOPROPYL(METHYL)PHOSPHINIC ACID HCL DIETHYLPHOSPHINIC ACID CGP 55845

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CGP 55845 (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinicacidhydrochloride CGP 55845 hydrochloride (2S)-3-[[(1S)-1-(3,4-DICHLOROPHENYL)ETHYL]AMINO-2-HYDROXYPROPYL](PHENYLMETHYL)PHOSPHINIC ACID benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid CGP 55845 hydrochlor 149184-22-5 C18H22Cl2NO3PHCl C18H23Cl3NO3P GABA/Glycine receptor