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clofexamide

clofexamide Structure
CAS No.
1223-36-5
Chemical Name:
clofexamide
Synonyms
ANP246;NP-246;IEM-455;ANP 246;ANP-246;clofexamide;Chlofexamide;Amichlophene;2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide;Acetamide, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]-
CBNumber:
CB0884312
Molecular Formula:
C14H21ClN2O2
Molecular Weight:
284.78
MOL File:
1223-36-5.mol
MSDS File:
SDS
Modify Date:
2023/7/12 17:21:22
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clofexamide Properties

Melting point 45 °C
Boiling point 124.5°C (rough estimate)
Density 1.1742 (rough estimate)
refractive index 1.5200 (estimate)
pka 14.19±0.46(Predicted)

SAFETY

Risk and Safety Statements

Toxicity LD50 oral in rat: 1040mg/kg

clofexamide Chemical Properties,Uses,Production

Originator

Clofexamide ,CNRS

Manufacturing Process

In 1 L of water there is dissolved 116.0 g (1 mole) of N,Ndiethylethylenediamine and, under vigorous stirring at a temperature maintained below 50°C, there is added 205.0 g (1 mole) of the chloride of pchlorphenoxyacetic acid. The solution becomes rapidly homogeneous; the formation of the basic amide hydrochloride is rapidly completed by further stirring the reaction mixture for 2 h at about 20°C. Then an excess of soda lye is added and the basic amide formed is extracted by ether. The ethereal solution is dried on anhydrous sodium sulfate and ether is distilled after that the residue is dried. So 2-(p-chlorophenoxy)-N-(2-(diethylamino)ethyl) acetamide is obtained.

Therapeutic Function

Antidepressant, Analgesic, Antiinflammatory, Local anesthetic

clofexamide Preparation Products And Raw materials

Raw materials

Water

Preparation Products

clofexamide Suppliers

Global( 7)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 15229059051 China 9976 58 Inquiry
Shaoguan Qicheng Biotechnology Co., Ltd 18122215013 China 1059 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23980 58 Inquiry
Shanghai New Union Textra Import & Export Co., Ltd +861-348-227-9455 China 2752 60 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 58
Shaoguan Qicheng Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai New Union Textra Import & Export Co., Ltd 60
Lanospharma Laboratories Co.,Ltd 56

1223-36-5(clofexamide )Related Search:

1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine 2-(2,4-Dichlorophenoxy)-N-(2-(diethylamino)ethyl)acetamide 3-{4-[(2,4-DICHLOROPHENOXY)ACETYL]PIPERAZIN-1-YL}-1,2-BENZISOTHIAZOLE 1,1-DIOXIDE 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide monohydrochloride 2-(2,4-Dichlorophenoxy)-N-(2-(4-morpholinyl)ethyl)acetamide
2-(4-Chlorophenoxy)-N-(2-(hexahydro-1H-azepin-1-yl)ethyl)acetamide hyd rochloride Acetamide, 2-(4-chlorophenoxy)-N-(2-(hexahydro-4-(phenylmethyl)-1H-1,4 -diazepin-1-yl)ethyl)-,dihydrochloride clofexamide FIPEXIDE HYDROCHLORIDE 2-(4-Chlorophenoxy)-N-(2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)ethy l)acetamide 2HCl
CLOFEZONE AURORA 11136 Erastin
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clofexamide 2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide Amichlophene Chlofexamide IEM-455 NP-246 ANP 246 ANP246 ANP-246 Acetamide, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]- 1223-36-5