Nemorubicin

CAS No.: 108852-90-0

Chemical Name:: Nemorubicin

Synonyms: MMRDX;DMM Dox;FCE 23762;PNU 152243;Nemorubicin;PNU-152243A;Nemorubicina;NeMorubincine;-Dichlorobenzophenone;Nemorubicin (PNU 152243)

CBNumber:: CB11179292

Molecular Formula:: C32H37NO13

Molecular Weight:: 643.64

MOL File:: 108852-90-0.mol

Modify Date:: 2024/7/2 8:54:59

Request For Quotation

Nemorubicin Properties

Boiling point	852.2±65.0 °C(Predicted)
Density	1.55±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:60.0(Max Conc. mg/mL);101.0(Max Conc. mM)
pka	7.35±0.60(Predicted)
form	Powder
color	Orange to reddish brown

Nemorubicin Chemical Properties,Uses,Production

Uses

Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition. Of note, Nemorubicin is active in cells with upregulation of the nucleotide excision repair (NER) pathway, where current therapies fail. Nemorubicin is biotransformed in the liver into cytotoxic metabolites that may further contribute to render this drug highly active against primary liver tumors or liver metastases.

Nemorubicin Preparation Products And Raw materials

Raw materials

Preparation Products

Nemorubicin Suppliers

Global( 76)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Hangzhou Benoy Chemical Co., Ltd	+8617342059697	China	315	58	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9338	55	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	China	9326	58	Inquiry
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.	+86-029-86333380 18829239519	China	923	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
GIHI CHEMICALS CO.,LIMITED	+8618058761490	China	49999	58	Inquiry

Supplier	Advantage
Hangzhou Benoy Chemical Co., Ltd	58
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
career henan chemical co	58
Baoji Guokang Bio-Technology Co., Ltd.	58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.	58
InvivoChem	58
TargetMol Chemicals Inc.	58
GIHI CHEMICALS CO.,LIMITED	58

Unlocking the Potential of Nemorubicin: Insights into Its Mechanism, Applications, and Storage
Nemorubicin, a powerful player in the arena of oncology, stands out for its significant contributions to cancer treatment.
May 14，2024

Nemorubicin:Metabolism and Pharmacokinetics, Cytotoxic Activity And Toxicity Studies
Nemorubicin is a member of the structural group of morpholinyl anthracyclines whose lead compounds were originally obtained by....
Feb 21，2023

108852-90-0(Nemorubicin)Related Search:

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2,4-DIMETHYL-2'-METHOXYBENZOPHENONE 2,4-DIMETHYL-3'-METHOXYBENZOPHENONE 2,5-DIMETHYL-3'-METHOXYBENZOPHENONE N-ETHYL-TETRAHYDRO-2H-PYRAN-4-AMINE 14-Hydroxy Carminomycin

2-METHOXY-3'-METHYLBENZOPHENONE ISLANDICIN Feudomycin A

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Nemorubicin 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-2,3,6-trideoxy-3-(2S)-2-methoxy-4-morpholinyl-.alpha.-L-lyxo-hexopyranosyloxy-, (8S,10S)- methoxy-morpholynil-doxorubicin NeMorubincine (1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 2,3,6-trideoxy-3-[(S)-2-methoxymorpholino]-alpha-L-lyxo-hexopyranoside DMM Dox FCE 23762 Methoxymorpholinyldoxorubicin MMRDX (1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranoside PNU152243A; PNU-152243A; PNU 152243A; NEMORUBICIN; METHOXYMORPHOLINYL-DOXORUBICIN PNU 152243 PNU-152243A Nemorubicin (PNU 152243) 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- 5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-a-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- FCE 23762,FCE-23762,PNU-152243,PNU152243,inhibit,Methoxymorpholinyl doxorubicin,Inhibitor,Nemorubicin,FCE23762 Nemorubicina -Dichlorobenzophenone 108852-90-0 108852-90-1 ≧99%