Bromfenac sodium
- CAS No.
- 91714-93-1
- Chemical Name:
- Bromfenac sodium
- Synonyms
- Bronuck;AHR 10282R;Ahr 10282b;Bromfenac Sodium b;bromfenacsodiumsal;bromfenac sodium salt;Bromfenac Sodium Base;Bromfenac sodium USP/EP/BP;Bromfenac Sodium (AHR 10282R);Bromfenac sodium(Diclofenac Impurity 11)
- CBNumber:
- CB1121670
- Molecular Formula:
- C15H11BrNNaO3
- Molecular Weight:
- 356.15
- MOL File:
- 91714-93-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:30:59
| Melting point | 285 ºC |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: ≥5mg/mL |
| form | powder |
| color | faint yellow to dark yellow |
| InChIKey | HZFGMQJYAFHESD-UHFFFAOYSA-M |
| CAS DataBase Reference | 91714-93-1 |
Bromfenac sodium price More Price(2)
Bromfenac sodium Chemical Properties,Uses,Production
Description
Bromfenac Sodium was launched in the US as a potent, orally-active, long lasting peripheral analgesic with antiinflammatory properties. It is structurally similar to ketoprofen and diclofenac and can be prepared in three steps from 2-amino-4’-bromophenone using Gassman’s oxindole synthesis. Duract’s biological effects are a result of its ability to reduce prostaglandin production through inhibition of cyclooxygenase. As a 4-bromo derivative of Amfenac, this modification increased the duration of analgesic activity and antiinflammatory potency. It was also free of any CNS, cardiovascular or autonomic effects. In comparison, 5 mg of Duract was equipotent to 650 mg of ASA and 25 mg was slightly more potent than 400 mg of Ibuprofen.
Uses
Bromfenac sodium has been used:
- to study its ability to bind to melanin
- in the synthesis of bromfenac indolinone standard
- to analyze its permeability in porcine conjunctiva
Definition
ChEBI: The sodium salt of bromfenac. Note that 'bromfenac sodium' commonly refers to the sesquihydrate (120638-55-3); this is the anhydrous form.
Bromfenac sodium Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Alkaloids Private Limited | +91-9866110664 +91-9866110664 | Telangana, India | 25 | 58 | Inquiry |
| Indoco Remedies Ltd | +91-2262871000 +91-2262871000 | Gujarat, India | 27 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Mylan Laboratories Ltd | +91-4023550543 +91-4030866666 | Telangana, India | 150 | 58 | Inquiry |
| Apicore Pharmaceuticals Pvt Ltd | +91-2662267177 +91-2662267166 | Gujarat, India | 181 | 58 | Inquiry |
| Vijaya Pharma And Life Science | +91-8939866271 +91-8939866271 | Tamil Nadu, India | 320 | 58 | Inquiry |
| Apionex Pharma Pvt Ltd | +91-9773830459 +91-9819236256 | Maharashtra, India | 26 | 58 | Inquiry |
| Enaltec Labs Pvt Ltd | +91-9167119247 +91-9167119247 | Maharashtra, India | 49 | 58 | Inquiry |
| Navone Specialties (OPC) Pvt Ltd | +91-9323789882 +91-9323789882 | Maharashtra, India | 151 | 58 | Inquiry |
| MYLAN API US LLC | 080 6672 8000 | New Delhi, India | 44 | 58 | Inquiry |
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