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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Neuronal Signaling >COX inhibitors >Bromfenac sodium

Bromfenac sodium

Bromfenac sodium Structure
  • ₹8086.28 - ₹32821.4
  • Product name: Bromfenac sodium
  • CAS: 91714-93-1
  • MF: C15H11BrNNaO3
  • MW: 356.15
  • EINECS:804-379-0
  • MDL Number:MFCD03701673
  • Synonyms:2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID SODIUM;2-Amino-3-(4-bromobenzoyl)phenylacetic acid sodium salt;Sodium [2-amino-3-(4-bromobenzoyl)phenyl]acetate;Ahr 10282b;Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, monosodium salt;Bronuck;2-{2-aMino-3-[(4-broMophenyl)carbonyl]phenyl}acetic acid;AHR 10282R
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0289
  • Product descriptionBromfenac sodium ≥98% (HPLC)
  • Packaging10MG
  • Price₹8086.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0289
  • Product descriptionBromfenac sodium ≥98% (HPLC)
  • Packaging50MG
  • Price₹32821.4
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0289 Bromfenac sodium ≥98% (HPLC) 10MG ₹8086.28 2022-06-14 Buy
Sigma-Aldrich(India) SML0289 Bromfenac sodium ≥98% (HPLC) 50MG ₹32821.4 2022-06-14 Buy

Properties

Melting point :285 ºC
storage temp. :2-8°C
solubility :H2O: ≥5mg/mL
form :powder
color :faint yellow to dark yellow
InChIKey :HZFGMQJYAFHESD-UHFFFAOYSA-M
CAS DataBase Reference :91714-93-1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

Bromfenac Sodium was launched in the US as a potent, orally-active, long lasting peripheral analgesic with antiinflammatory properties. It is structurally similar to ketoprofen and diclofenac and can be prepared in three steps from 2-amino-4’-bromophenone using Gassman’s oxindole synthesis. Duract’s biological effects are a result of its ability to reduce prostaglandin production through inhibition of cyclooxygenase. As a 4-bromo derivative of Amfenac, this modification increased the duration of analgesic activity and antiinflammatory potency. It was also free of any CNS, cardiovascular or autonomic effects. In comparison, 5 mg of Duract was equipotent to 650 mg of ASA and 25 mg was slightly more potent than 400 mg of Ibuprofen.

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