5-Bromoisatin

5-Bromoisatin Structure
CAS No.
87-48-9
Chemical Name:
5-Bromoisatin
Synonyms
5-BROMOINDOLINE-2,3-DIONE;BromoIsatin;5-bromisatin;5-BROMO-3-CHLORO-2-METHYLPYRIDINE;NSC 4980;AKOS B028934;5-BROMOISATIN;5-bromo-isati;AKOS BBS-00000997;BUTTPARK 50\07-94
CBNumber:
CB1142138
Molecular Formula:
C8H4BrNO2
Molecular Weight:
226.03
MOL File:
87-48-9.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:43

5-Bromoisatin Properties

Melting point 247-252 °C (lit.)
Density 1.7498 (rough estimate)
refractive index 1.6120 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in N,N dimethylformamide.
pka 8.74±0.20(Predicted)
form Crystalline Powder
color Orange
BRN 383760
InChIKey MBVCESWADCIXJN-UHFFFAOYSA-N
CAS DataBase Reference 87-48-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  37/38-41
Safety Statements  26-36/39-37/39-36
RIDADR  2811
WGK Germany  2
RTECS  NL7875000
Hazard Note  Irritant
HS Code  29337900
NFPA 704
1
2 0

5-Bromoisatin price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 476994 5-Bromoisatin technical grade, 90% 87-48-9 5G ₹3453.18 2022-06-14 Buy
Sigma-Aldrich(India) 476994 5-Bromoisatin technical grade, 90% 87-48-9 25G ₹11301.3 2022-06-14 Buy
TCI Chemicals (India) B1566 5-Bromoisatin 87-48-9 25G ₹7300 2022-05-26 Buy
Product number Packaging Price Buy
476994 5G ₹3453.18 Buy
476994 25G ₹11301.3 Buy
B1566 25G ₹7300 Buy

5-Bromoisatin Chemical Properties,Uses,Production

Chemical Properties

Orange crystalline powder

Uses

5-Bromoisatin is used in the synthesis of N-derivatives of 5-bromoisatin, N-substituted pyrroles, linear polyaryleneoxindoles, 5-bromodioxindole, cinchoninic acid derivatives, 3-hydroxyoxindole, S-benzyldithiocarbazate Schiff Bases, 5-bromooxindole and Morita-Baylis-Hillman adducts of isatin derivatives. It is an indole derivative.

General Description

5-Bromoisatin is a 5-haloisatin. One of the methods reported for its synthesis is by reacting N-halosaccharins with isatin in the presence of SiO2. Its inotropic activity has been studied on rhythmically stimulated papillary muscles of guinea pigs. It is reported to exhibit analgesic and sedative properties at a dose of 0.2g/kg in mice.

Purification Methods

5-Bromoisatin forms red prisms or needles from EtOH. The N-acetate crystallises as yellow prisms from *C6H6, m 170-172o, and the N-methyl derivative forms orange-red needles from MeOH, m 172-173o. [Heller Chem Ber 53 1545 1920, Buu-Hoi Recl Trav Chim, Pays-Bas 73 197 1954, Baker etal. Tetrahedron Lett 215 1978, Beilstein 21 H 453, 21 III/IV 5009.]

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5-Bromoindoline-2,3-dione, tech 5 - broMine indigo red 5-Bromoisatin technical grade, 90% NSC 4980 5-BroMoisatin , 96.0%(LC&T 5-BROMO-1H-INDOLE-2,3-DIONE 5-BROMOISATIN 5-BROMOISATIN HEMIHYDRATE 5-BROMOISATIN, TECH., 90% 5-Bromoisatin,tech.90% AKOS BBS-00000997 AKOS B028934 5-BROMOISATIN, 98+% 5-Bromoisatin, 90+% 5-BROMOINDOLE-2,3-DIONE 5-BROMOINDOLE-2,3-DIONE HEMIHYDRATE BUTTPARK 50\07-94 1H-Indole-2,3-dione,5-bromo- 5-bromo-1h-indole-3-dione 5-bromo-indole-3-dione 5-bromo-isati 5-BroMoisatin (LC&T Reaxys ID: 383760 5-Bromoisatin > 5-BROMOINDOLINE-2,3-DIONE BromoIsatin 5-BROMO-3-CHLORO-2-METHYLPYRIDINE 5-bromisatin 8-Morpholineethanamine,N-(cyclohexylcarbonimidoyl)- 1H-Pyrazole-5-carboxylicacid,1-methyl-3-(6-methylethyl)- 87-48-9 C8H4BrNO2xH2O C8H4BrNO2 Halogenated Heterocycles Heterocyclic Building Blocks Simple Indoles Indoles ARYL HALIDE Building Blocks Indoles Aromatics Heterocycles Indole/indoline/oxindole Indole and Indoline Indane/Indanone and Derivatives Simple Indoles Halogenated Heterocycles Heterocyclic Building Blocks IndolesBuilding Blocks