9-keto Fluprostenol isopropyl ester
- CAS No.
- 1219032-18-4
- Chemical Name:
- 9-keto Fluprostenol isopropyl ester
- Synonyms
- Travoprost 12;9-ketotrevoprost;9-Keto Travoprost;Travoprost Impurity 21;Travoprost Impurity 35;9-KETO FLUPROSTENOL ISOPROPYL ESTER;FLUPROSTENOL PROSTAGLANDIN E2 ISOPROPYL ESTER;Travoprost Impurity 16（9-keto Fluprostenol Isopropyl Ester）;(+)-9-OXO-11ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC-ACID, ISOPROPYL ESTER;5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-5-oxocyclopentyl]-, 1-methylethyl ester, (5Z)-
- CBNumber:
- CB1143711
- Molecular Formula:
- C26H33F3O6
- Molecular Weight:
- 498.53
- MOL File:
- Mol file
- Modify Date:
- 2023/6/8 9:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
9-keto Fluprostenol isopropyl ester Chemical Properties,Uses,Production
Uses
Fluprostenol is a well-studied, potent analog of prostaglandin F2α (PGF2α) and acts primarily through the FP receptor. 9-keto Fluprostenol is an analog of PGE2 with structural modifications intended to give it a prolonged half-life and greater potency. 9-keto Fluprostenol isopropyl ester has the potential to act as an EP agonist in prodrug form. However, no studies on the pharmacology of this compound have been published to date. In addition 9-keto fluprostenol isopropyl ester is a potential metabolite of Travoprost, which is the Alcon trade name for fluprostenol isopropyl ester. In monkey cornea, this transformation was observed as a product of NADP+-dependent 15-hydroxyprostaglandin dehydrogenase when the closely related analog Latanoprost was used as a substrate. Certain F-series prostaglandins have been shown to be converted to the corresponding E-series compounds in rabbit liver and human platelet preparations.
9-keto Fluprostenol isopropyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | China | 11922 | 58 | Inquiry |
| Cayman Chemical Company | (800) 364-9897 | United States | 6213 | 81 | Inquiry |
| TOSUN PHARM | 020-61855200 13326451905 | China | 7883 | 58 | Inquiry |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016; 18162595016 | China | 9119 | 58 | Inquiry |
| Hubei Yangxin Medical Technology Co., Ltd. | 15374522761 | China | 8976 | 55 | Inquiry |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9803 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 15002134094 | China | 23248 | 58 | Inquiry |
| Nantong Hanfang Biotechnology Co. , Ltd. | hanfangpharma@126.com; 18616537568 | China | 29964 | 58 | Inquiry |
| Hubei Moco Chemical Co., Ltd. | 18627753421; 18627756402 | China | 19365 | 58 | Inquiry |