4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)-

CAS No.: 324519-68-8

Chemical Name:: 4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)-

Synonyms: Aliskiren inter-4;5-CHLORO-2-ISOPROPYL-N, N-DIMETHYLPENT-4-ENAMIDE;5-chloro-N,N-dimethyl-2-propan-2-yl-4-pentenamide;(E)-5-chloro-2-isopropyl-N,N-diMethylpent-4-enaMide;5-Chloro-2-isopropyl-pent-4-enoic acid dimethylamide;(S,E)-5-chloro-2-isopropyl-N,N-dimethylpent-4-enamide;5-Chloro-2S-isopropyl-pent-4-enoic acid dimethylamide;(E,2S)-5-Chloro-2-isopropyl-N,N-dimethyl-pent-4-enamide;(2S,4E)-5-Chloro-2-isopropyl-N,N-dimethylpent-4-enamide;(2S,4E)-5-chloro-N,N-dimethyl-2-(propan-2-yl)pent-4-enamide

CBNumber:: CB11465773

Molecular Formula:: C10H18ClNO

Molecular Weight:: 203.71

MOL File:: 324519-68-8.mol

MSDS File:: SDS

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4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Properties

Boiling point	277 ºC
Density	0.999
Flash point	121 ºC
storage temp.	2-8°C
pka	-0.58±0.70(Predicted)
CAS DataBase Reference	324519-68-8(CAS DataBase Reference)

4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Chemical Properties,Uses,Production

Uses

(2S,4E)-5-Chloro-2-isopropyl-N,N-dimethylpent-4-enamide is an intermediate in the preparation of orally active renin inhibitor Aliskiren (A536000).

4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Preparation Products And Raw materials

Raw materials

4-Pentenoic acid, 5-chloro-2-(1-methylethyl)-, methyl ester, (4E)- (S,E)-ethyl 5-chloro-2-isopropylpent-4-enoate (1,3-Dioxane-4,6-dione, 2,2-diMethyl-5-(1-Methylethyl)) Propanedioic acid, 2-[(2E)-3-chloro-2-propen-1-yl]-2-(1-methylethyl)-, 1,3-dimethyl ester 2-Isopropylmalonic acid dimethyl ester

Aliskiren inter-11 4-Pentenoic acid, 5-chloro-2-(1-methylethyl)-, (2S,4E)- Dimethylamine Dimethylamine hydrochloride

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Preparation Products

4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Suppliers

Global( 51)Suppliers

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KKyemistry (India) Pvt. Ltd.	+91 (40) 2351-0950	New Delhi, India	197	50	Inquiry
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Trignokem International	+91 (40) 2717-0709	New Delhi, India	380	50	Inquiry
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Supplier	Advantage
KKyemistry (India) Pvt. Ltd.	50
Manus Aktteva	34
Trignokem International	50
A.J Chemicals	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

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5-Chloro-2-isopropyl-pent-4-enoic acid dimethylamide (2S,4E)-5-Chloro-N,N-dimethyl-2-(1-methylethyl)-4-pentenamide 4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Aliskiren inter-4 (E)-(S)-5-chloro-2-isopropyl-pent-4-enoic acid dimethylamide (S,E)-5-chloro-2-isopropyl-N,N-dimethylpent-4-enamide 5-CHLORO-2-ISOPROPYL-N, N-DIMETHYLPENT-4-ENAMIDE (E)-5-chloro-2-isopropyl-N,N-diMethylpent-4-enaMide (2S,4E)-5-Chloro-2-isopropyl-N,N-dimethylpent-4-enamide 5-Chloro-2S-isopropyl-pent-4-enoic acid dimethylamide (E,2S)-5-Chloro-2-isopropyl-N,N-dimethyl-pent-4-enamide 5-chloro-N,N-dimethyl-2-propan-2-yl-4-pentenamide (2S,4E)-5-Chloro-N,N-dimethyl-2-(1-methylethyl)-4-pentenamid... (2S,4E)-5-chloro-N,N-dimethyl-2-(propan-2-yl)pent-4-enamide 324519-68-8 Drug Intermediates Aliskiren Intermediate