RUFLOXACIN
- CAS No.
- 101363-10-4
- Chemical Name:
- RUFLOXACIN
- Synonyms
- Qari;Mones;Tebraxin;ISF-09334;RUFLOXACIN;4]thiazino[2;AKOS NCG1-0068;3-dihydro-7H-[1;RUFLOXACIN USP/EP/BP;4-ij]quinoline-6-carboxylic acid
- CBNumber:
- CB1240991
- Molecular Formula:
- C17H18FN3O3S
- Molecular Weight:
- 363.41
- MOL File:
- 101363-10-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/4 17:34:30
| Boiling point | 574.6±50.0 °C(Predicted) |
|---|---|
| Density | 1.54 |
| storage temp. | 2-8°C |
| pka | 5.21±0.20(Predicted) |
| CAS DataBase Reference | 101363-10-4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H302-H315-H319 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
RUFLOXACIN Chemical Properties,Uses,Production
Pharmaceutical Applications
A tricyclic fluoroquinolone formulated as the hydrochloride salt. It is inactive against Gram-positive cocci with MICs >2 mg/L. It displays weak activity in vitro against Enterobacteriaceae with the MIC for most species >1 mg/L. Activity against Ps. aeruginosa is poor (MIC 16–32 mg/L). After loading doses of 400 and 600 mg followed with 9 days of either 200 or 300 mg, mean peak plasma levels were around 4.5–7 mg/L, respectively. The mean apparent elimination halflife was 44 h. Approximately 50% is eliminated in the urine.
It has been used in urinary tract infection and chronic prostatitis, but clinical experience is limited.
RUFLOXACIN Preparation Products And Raw materials
Raw materials
ETHYL THIOGLYCOLATE
2,3,4-TRICHLORONITROBENZENE
Ethyl benzoylacetate
2,3,4,5-Tetrafluorobenzoic acid
thiazine
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RUFLOXACIN Suppliers
Global( 38)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25808 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 4008200310 | China | 24017 | 58 | Inquiry |
| Energy Chemical | 021-58432009 400-005-6266 | China | 44843 | 58 | Inquiry |
| Aikon International Limited | 025-66113011 18112977050 | China | 16028 | 58 | Inquiry |
| Chengdu HuaNa Chemicals Co., Ltd. | 028-86612776; 13699069380 | China | 966 | 55 | Inquiry |
| BOC Sciences | 1-631-485-4226; 16314854226 | United States | 14059 | 65 | Inquiry |
| AKos Consulting & Solutions GmbH | +49 7627 970068 | Germany | 6723 | 72 | Inquiry |
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101363-10-4(RUFLOXACIN)Related Search:
RUFLOXACIN
ISF-09334
AKOS NCG1-0068
8-FLUORO-9-(4-METHYL-PIPERAZIN-1-YL)-6-OXO-2,3-DIHYDRO-6H-1-THIA-3A-AZA-PHENALENE-5-CARBOXYLIC ACID
9-Fluom-2，3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1，2，3-de]-1，4-benzothiazine-6-carboxylic acid
Mones
Qari
Tebraxin
9-Fluoro-2,3-dihydro-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid
7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-
RUFLOXACIN USP/EP/BP
3-dihydro-7H-[1
4]thiazino[2
4-ij]quinoline-6-carboxylic acid
9-Fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2
101363-10-4
C17H18FN3O3S
ACTIVE PHARMACEUTICAL INGREDIENTS