6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine
- CAS No.
- 1262888-28-7
- Chemical Name:
- 6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine
- Synonyms
- C43;CS-1649;Spautin-1;SPAUTIN-1;SPAUTIN1;Spautin 1 - MBCQ derivative C43;4-((4-Fluorobenzyl)amino)-6-fluoroquinazoline;6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine;6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine;6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine 98+%;6-Fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine
- CBNumber:
- CB12658835
- Molecular Formula:
- C15H11F2N3
- Molecular Weight:
- 271.26
- MOL File:
- 1262888-28-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 211 °C |
|---|---|
| Boiling point | 419.6±40.0 °C(Predicted) |
| Density | 1.366±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble15mg/mL (clear solution) |
| pka | 5.75±0.50(Predicted) |
| form | powder |
| color | white to beige |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2922390090 | |||||||||
| NFPA 704 |
|
6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0440 | Spautin-1 ≥98% (HPLC) | 1262888-28-7 | 5MG | ₹12609.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0440 | Spautin-1 ≥98% (HPLC) | 1262888-28-7 | 25MG | ₹51348.6 | 2022-06-14 | Buy |
| TCI Chemicals (India) | P2613 | Spautin-1 min. 98.0 % | 1262888-28-7 | 10MG | ₹3200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | P2613 | Spautin-1 min. 98.0 % | 1262888-28-7 | 50MG | ₹8800 | 2022-05-26 | Buy |
6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine Chemical Properties,Uses,Production
Uses
Spautin-1 is a potent pharmacological autophagy inhibitor that promotes UVB-induced tumorigenesis. It is also a small-molecule drug that modulate autophagic pathways in different types of cancer.
Biochem/physiol Actions
Spautin-1 inhibits the activity of two ubiquitin-specific peptidases, USP10 and USP13, causing an increase in proteasomal degradation of class III PI3 kinase complexes, which have been shown to regulate autophagy.
6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 102)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | United States | 19639 | 58 | Inquiry |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
1262888-28-7(6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine)Related Search:
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6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine
6-Fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine
C43
4-((4-Fluorobenzyl)amino)-6-fluoroquinazoline
Spautin-1
6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine
6-Fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine
Spautin 1 - MBCQ derivative C43
CS-1649
SPAUTIN-1;SPAUTIN1
6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine 98+%
4-Quinazolinamine, 6-fluoro-N-[(4-fluorophenyl)methyl]-
1262888-28-7
Inhibitors