6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine
|
- ₹3200 - ₹51348.6
- Product name: 6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine
- CAS: 1262888-28-7
- MF: C15H11F2N3
- MW: 271.26
- EINECS:
- MDL Number:MFCD16962292
- Synonyms:6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine;6-Fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine;C43;4-((4-Fluorobenzyl)amino)-6-fluoroquinazoline;Spautin-1;6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine;6-Fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine;Spautin 1 - MBCQ derivative C43
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 25MG
- 50MG
- ManufacturerTCI Chemicals (India)
- Product numberP2613
- Product descriptionSpautin-1 min. 98.0 %
- Packaging10MG
- Price₹3200
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberP2613
- Product descriptionSpautin-1 min. 98.0 %
- Packaging50MG
- Price₹8800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0440
- Product descriptionSpautin-1 ≥98% (HPLC)
- Packaging5MG
- Price₹12609.6
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0440
- Product descriptionSpautin-1 ≥98% (HPLC)
- Packaging25MG
- Price₹51348.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | P2613 | Spautin-1 min. 98.0 % | 10MG | ₹3200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | P2613 | Spautin-1 min. 98.0 % | 50MG | ₹8800 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SML0440 | Spautin-1 ≥98% (HPLC) | 5MG | ₹12609.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0440 | Spautin-1 ≥98% (HPLC) | 25MG | ₹51348.6 | 2022-06-14 | Buy |
Properties
Melting point :211 °C
Boiling point :419.6±40.0 °C(Predicted)
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL (clear solution)
pka :5.75±0.50(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :419.6±40.0 °C(Predicted)
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL (clear solution)
pka :5.75±0.50(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
| Symbol(GHS): |
 
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
Spautin-1 is an autophagy inhibitor, inducing cell death in human breast cancer Bcap-37 cells grown in glucose-free media (EC50 = ~1.25 μM). It does not significantly affect the viability of Bcap-37 cells grown in complete media. Spautin-1 promotes the degradation of Vps34 PI3K complex by inhibiting the deubiquitinating enzymes USP10 and USP13 (IC50s = 0.58 and 0.69 μM, respectively). It is used to elucidate the role of autophagy in cellular processes. Spautin-1 has also been used to demonstrate roles for autophagy in viral infection.More related product prices
ABT-199 NS-398 3-Methyl-1-pentyn-3-ol STF-62247 YM155 Hydroxychloroquine sulfate MIF Antagonist, ISO-1Related product price
- NS-398
₹3609-97035.3 - 3-Methyl-1-pentyn-3-ol
₹1700-2305.73 - STF-62247
₹11730-15923.58