4-DesMethyl Istradefylline

4-DesMethyl Istradefylline Structure
CAS No.
160434-48-0
Chemical Name:
4-DesMethyl Istradefylline
Synonyms
Itraphylline impurities6;4-Desmethyl Istradefylline;Istradefylline Impurity 14;Itraphylline impurities869;Istradefylline M1 metabolite;4-DesMethyl Istradefylline impurity;Istradefylline 4-O-Desmethyl Impurity;(E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione;1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI)
CBNumber:
CB12695351
Molecular Formula:
C19H22N4O4
Molecular Weight:
370.4
MOL File:
160434-48-0.mol
MSDS File:
SDS
Modify Date:
2024/3/21 17:31:59

4-DesMethyl Istradefylline Properties

Boiling point 604.8±65.0 °C(Predicted)
Density 1.30±0.1 g/cm3(Predicted)
pka 9.88±0.31(Predicted)

4-DesMethyl Istradefylline Chemical Properties,Uses,Production

Uses

4-Desmethyl Istradefylline is an impurity of Istradefylline (I927000), a selective A(2A) antagonist used in the treatment of Parkinson’s disease. 4-Desmethyl Istradefylline have also been shown to exhibit inhibitory potency towards adenosine A2A receptors and is classified as its an adenosine A2A receptor antagonist.

4-DesMethyl Istradefylline Preparation Products And Raw materials

Raw materials

Preparation Products

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(E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione 4-DesMethyl Istradefylline impurity Istradefylline Impurity 14 1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI) Istradefylline 4-O-Desmethyl Impurity Istradefylline M1 metabolite Itraphylline impurities869 Itraphylline impurities6 4-Desmethyl Istradefylline 160434-48-0 Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals