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Bambuterol

Bambuterol Structure
CAS No.
81732-65-2
Chemical Name:
Bambuterol
Synonyms
CS-1238;BAMBUTEROL;BAMBUTEROLE HCL;Bambuterol USP/EP/BP;Bambuterol ((±)-Bambuterol);Bambuterol & Bambuterol Hydrochloride;5-[2-(ter-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate);[3-(Dimethylcarbamoyloxy)-5-[1-hydroxy-2-(tert-butylamino)ethyl]phenyl]N,N-dimethylcarbamate;Bis(dimethylcarbamic acid)5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester;[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate
CBNumber:
CB1298679
Molecular Formula:
C18H29N3O5
Molecular Weight:
367.45
MOL File:
81732-65-2.mol
Modify Date:
2023/5/21 10:59:17

Bambuterol Properties

Boiling point 500.9±50.0 °C(Predicted)
Density 1.154±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility H2O: ~33 mg/mL, soluble
pka 13.70±0.20(Predicted)
form powder
color off-white
CAS DataBase Reference 81732-65-2

SAFETY

Risk and Safety Statements

WGK Germany  3
Toxicity LDLo ipr-mus: 0.3 mg/kg JPETAB 293,896,2000

Bambuterol Chemical Properties,Uses,Production

Description

Bambuterol is a new once-daily, oral bronchodilator especially useful in the chronic treatment of nocturnal asthma. It is a prodrug slowly converted by hydrolysis in the lung tissue to terbutaline, generating long-acting bronchodilation with comparable side effects.

Definition

ChEBI: A carbamate ester that is terbutaline in which both of the phenolic hydroxy groups have been protected as the corresponding N,N-dimethylcarbamates. A long acting beta-adrenoceptor agonist used in the treatment of asthm , it is a prodrug for terbutaline.

Hazard

A poison.

Safety Profile

A poison by intraperitoneal route.When heated to decomposition it emits toxic vapors ofNOx.

Bambuterol Preparation Products And Raw materials

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OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
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MedChemExpress 021-58955995 United States 6398 58 Inquiry
BAMBUTEROL [3-(Dimethylcarbamoyloxy)-5-[1-hydroxy-2-(tert-butylamino)ethyl]phenyl]N,N-dimethylcarbamate Bis(dimethylcarbamic acid)5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester [3-[2-(tert-butylamino)-1-hydroxy-ethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate N,N-dimethylcarbamic acid [3-[2-(tert-butylamino)-1-hydroxy-ethyl]-5-(dimethylcarbamoyloxy)phenyl] ester Bambuterol & Bambuterol Hydrochloride BAMBUTEROLE HCL 5-[2-(ter-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate) Bambuterol ((±)-Bambuterol) CS-1238 Carbamic acid, N,N-dimethyl-, C,C'-[5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene] ester Bambuterol USP/EP/BP N,N-dimethylcarbamic acid [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-[dimethylamino(oxo)methoxy]phenyl] ester 81732-65-2 C18H29N3O5