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Hexapeptide-11

Hexapeptide-11 Structure
CAS No.
161258-30-6
Chemical Name:
Hexapeptide-11
Synonyms
Hexapeptide-11;H-Phe-Val-Ala-Pro-Phe-Pro-OH;L-Proline, L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-;(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
CBNumber:
CB13134442
Molecular Formula:
C36H48N6O7
Molecular Weight:
676.8
MOL File:
161258-30-6.mol
MSDS File:
SDS
Modify Date:
2024/6/11 18:14:38

Hexapeptide-11 Properties

Boiling point 1035.1±65.0 °C(Predicted)
Density 1.269±0.06 g/cm3(Predicted)
pka 3.43±0.20(Predicted)
InChIKey GFEYWOGCSROPRT-OBXVVNIGSA-N
SMILES C(O)(=O)[C@@H]1CCCN1C(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=CC=C1)N

Hexapeptide-11 Chemical Properties,Uses,Production

Description

Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts.

Uses

Hexapeptide-11 reduces the appearance of fine lines and wrinkles, making this an excellent addition to all kinds of skin care and anti-aging products. It has a unique set of amino acids that help to manipulate collagen levels and boost elasticity in the skin.

Physiological effects

Exposure of fibroblasts to Hexapeptide-11 promoted dose and time-dependent activation of proteasome, autophagy, chaperones and antioxidant responses related genes. Moreover, it promoted increased nuclear accumulation of Nrf2; higher expression levels of proteasomal protein subunits and increased proteasome peptidase activities. In line with these findings we noted that Hexapeptide-11 conferred significant protection in fibroblasts against oxidative-stress-mediated premature cellular senescence, while at in vivo skin deformation assays in human subjects it improved skin elasticity.

Hexapeptide-11 Preparation Products And Raw materials

Raw materials

Preparation Products

Hexapeptide-11 Suppliers

Global( 70)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shanghai Likang New Materials Co., Limited +86-16631818819 +86-17736933208 China 9311 58 Inquiry
Hebei Kingfiner Technology Development Co.Ltd +86-15532196582 +86-15373005021 China 2990 58 Inquiry
Wuhan Haorong Biotechnology Co.,ltd +86-18565342920; +8618565342920 China 289 58 Inquiry
zhuzhou dingcheng meihei comestic co.,ltd +8618873369619 China 260 58 Inquiry
Hangzhou Hyper Chemicals Limited +86-0086-57187702781 +8613675893055 China 295 58 Inquiry
Shanghai Getian Industrial Co., LTD +86-15373193816 +86-15373193816 China 269 58 Inquiry
Strong peptide cross-border e-commerce Co. LTD +undefined13930052870 China 84 58 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10311 58 Inquiry
Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-0519-85551759 +8613506123987 China 8836 58 Inquiry

Related articles

Hexapeptide-11 (2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid L-Proline, L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl- H-Phe-Val-Ala-Pro-Phe-Pro-OH 161258-30-6 C36H48N6O7