Betamethasone 17-valerate
![Betamethasone 17-valerate Structure](CAS/GIF/2152-44-5.gif)
- CAS No.
- 2152-44-5
- Chemical Name:
- Betamethasone 17-valerate
- Synonyms
- BETAMETHASONE VALERATE;VALISONE;Betaderm;BETNOVATE;BETHAMETASONE VALERATE;Luxiq;Betoid;Valison;9α-Fluo;Deviphos
- CBNumber:
- CB1317879
- Molecular Formula:
- C27H37FO6
- Molecular Weight:
- 476.58
- MOL File:
- 2152-44-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/8 18:06:34
Melting point | 183-184° |
---|---|
alpha | D +77° (dioxane) |
Boiling point | 598.9±50.0 °C(Predicted) |
Density | 1.1174 (estimate) |
storage temp. | 2-8°C |
solubility | Practically insoluble in water, freely soluble in acetone and in methylene chloride, soluble in ethanol (96 per cent). |
form | Solid |
pka | 12.90±0.70(Predicted) |
color | White |
Merck | 13,1183 |
BRN | 4240001 |
InChIKey | SNHRLVCMMWUAJD-SUYDQAKGSA-N |
SMILES | [C@]12(C)C[C@@H]([C@]3(F)[C@@]4(C)C=CC(=O)C=C4CC[C@@]3([H])[C@]1([H])C[C@H](C)[C@@]2(C(=O)CO)OC(=O)CCCC)O |&1:0,3,4,6,16,18,21,23,r| |
CAS DataBase Reference | 2152-44-5(CAS DataBase Reference) |
EPA Substance Registry System | .beta.-Methasone 17-valerate (2152-44-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H360D-H373 | |||||||||
Precautionary statements | P201-P202-P260-P280-P308+P313-P405 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 48 | |||||||||
Safety Statements | 22-24/25 | |||||||||
RTECS | TU3835000 | |||||||||
HS Code | 2937229000 | |||||||||
Toxicity | mouse,LD50,intraperitoneal,632mg/kg (632mg/kg),Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. | |||||||||
NFPA 704 |
|
Betamethasone 17-valerate price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | B0515 | Betamethasone 17-valerate | 2152-44-5 | 25MG | ₹10294.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | B0515 | Betamethasone 17-valerate | 2152-44-5 | 100MG | ₹28209.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1780 | Betamethasone Valerate Pharmaceutical Secondary Standard; Certified Reference Material | 2152-44-5 | 1G | ₹28383.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | B0515 | Betamethasone 17-valerate | 2152-44-5 | 500MG | ₹86361.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 46074 | Betamethasone 17-valerate VETRANAL?, analytical standard | 2152-44-5 | 250MG | ₹8779.08 | 2022-06-14 | Buy |
Betamethasone 17-valerate Chemical Properties,Uses,Production
Description
Betamethasone 17-valerate is a synthetic glucocorticoid ester. It is the 17-valerate ester of betamethasone. Betamethasone 17-valerate is often used to treat mild eczema with good efficacy and lower incidence of steroid induced adverse effects due to its lower potency compared to other glucocorticoids. It is available in cream, ointment, lotion, and foam preparations for topical use.
Chemical Properties
White Solid
Uses
Betamethasone 17-Valerate is a glucocorticoid with anti-inflammatory properties and immunosuppressive activity. It is an antiepileptic non-selective phosphodiesterase inhibitor. Topical application of Betamethasone 17-Valerate has been shown to inhibit heat-induced vasodilatation in man. As a medium-strength corticosteroid, this medication is used to treat a variety of skin conditions (such as eczema, dermatitis, allergies, rash). Betamethasone reduces the swelling, itching, and redness that can occur in these types of conditions.
Indications
Betamethasone valerate (Psorion, Beta-Val, Luxiq) is a synthetic fluorinated corticosteroid.
Definition
ChEBI: Betamethasone valerate is a steroid ester that is betamethasone in which the hydroxy group at the 17alpha position has been converted to the corresponding pentanoate ester. It has a role as an anti-inflammatory drug. It is a steroid ester, a 20-oxo steroid, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a primary alpha-hydroxy ketone. It is functionally related to a betamethasone.
Betamethasone 17-valerate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Halcyon Labs Pvt. Ltd | +919833750169 | Mumbai, India | 17 | 58 | Inquiry |
OPULENT PHARMA | +91-9106692785 +91-9106692785 | Gujarat, India | 479 | 58 | Inquiry |
Enzal Chemicals India Limited | +91-9930897773 +91-9930897773 | New Delhi, India | 25 | 58 | Inquiry |
Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
Anuh Pharma Ltd (SK GROUP) | +912266227575 | Maharashtra, India | 38 | 58 | Inquiry |
Agro Cool India Ltd | +91 9999464006 | New Delhi, India | 11 | 58 | Inquiry |
Stermone Chemicals Pvt Ltd | +91-9328939700 +91-9328939700 | Gujarat, India | 20 | 58 | Inquiry |
Maharshi Pharma Chem | +91-7940359347 +91-7433927173 | Gujarat, India | 24 | 58 | Inquiry |
Prachem Laboratories | +91-7948993109 +91-7383072020 | Gujarat, India | 44 | 58 | Inquiry |
Horster Biotek Pvt Ltd | +91-7359657360 +91-9898127219 | Gujarat, India | 58 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Halcyon Labs Pvt. Ltd | 58 |
OPULENT PHARMA | 58 |
Enzal Chemicals India Limited | 58 |
Gonane Pharma | 58 |
Anuh Pharma Ltd (SK GROUP) | 58 |
Agro Cool India Ltd | 58 |
Stermone Chemicals Pvt Ltd | 58 |
Maharshi Pharma Chem | 58 |
Prachem Laboratories | 58 |
Horster Biotek Pvt Ltd | 58 |
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