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BECLOMETHASONE

BECLOMETHASONE Structure
CAS No.
4419-39-0
Chemical Name:
BECLOMETHASONE
Synonyms
Beclometasone;BecL;Becolvent;omethasone;BECLOMETHASONE;BecloMethasone Solution;Beclomethasone - 95% min;Beclomethasone - 98% min;BECLOMETHASONE USP/EP/BP;Beclomethasone in Methanol
CBNumber:
CB7694093
Molecular Formula:
C22H29ClO5
Molecular Weight:
408.92
MOL File:
4419-39-0.mol
Modify Date:
2024/3/19 15:37:50

BECLOMETHASONE Properties

Melting point 217- 222°C (dec.)
Boiling point 600.2±55.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Dioxane (Sparingly, Sonicated), DMSO (Sparingly), Ethyl Acetate (Slightly), Methane
form Solid
pka 12.17±0.70(Predicted)
color White to Pale Beige
Merck 13,1020
Stability Hygroscopic
CAS DataBase Reference 4419-39-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501
Safety Statements  24/25
WGK Germany  3
HS Code  29372900

BECLOMETHASONE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) B0385 Beclomethasone ≥99% 4419-39-0 100MG ₹24702.65 2022-06-14 Buy
Sigma-Aldrich(India) B0385 Beclomethasone ≥99% 4419-39-0 250MG ₹48755.8 2022-06-14 Buy
Sigma-Aldrich(India) B0385 Beclomethasone ≥99% 4419-39-0 1G ₹128395.33 2022-06-14 Buy
Product number Packaging Price Buy
B0385 100MG ₹24702.65 Buy
B0385 250MG ₹48755.8 Buy
B0385 1G ₹128395.33 Buy

BECLOMETHASONE Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

Glucocorticoid. Beclomethasone is used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).

Definition

ChEBI: A 17alpha-hydroxy steroid that is prednisolone in which the hydrogens at the 9alpha and 16beta positions are substituted by a chlorine and a methyl group, respectively.

Biological Functions

The topical anti-inflammatory potency for beclomethasone dipropionate (BDP) is approximately 5,000 times greater than hydrocortisone, 500 times greater than betamethasone or dexamethasone, and approximately five times greater than fluocinolone acetonide or triamcinolone acetonide, as measured by vasoconstrictor assay.

Clinical Use

Beclomethasone, a 9α-chloro analogue of betamethasone, is a potent glucocorticoid with approximately half the potency of its fluoro analogue. It is used topically as its dipropionate derivative in inhalation aerosol therapy for asthma and rhinitis but not for treatment of steroid-responsive dermatoses.

BECLOMETHASONE Preparation Products And Raw materials

Global( 133)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Anant Pharmaceuticals Pvt Ltd +91-8550986868 +91-9485998001 Haryana, India 461 58 Inquiry
GLP Pharma Standards +91 9866074638 Hyderabad, India 1644 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hunan Jibang Biological Technology Co., LTD +8613776644403 China 1806 58 Inquiry
Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11beta,16beta)- 9alpha-Chloro-16beta-methylprednisolone 9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 9-Chloro-11beta,17,21-trihydroxy-16beta-methyl-pregna-1,4-diene-3,20-dione Beclomethasone Solution, 100ppm 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione Beclomethasone solution,1000ppm 1,4-PREGNADIEN-9-ALPHA-CHLORO-16-BETA-METHYL-11-BETA, 17-ALPHA, 21-TRIOL-3,20-DIONE 9ALPHA-CHLORO-16BETA-METHYL-1,4-PREGNADIENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE BECLOMETHASONE BeclomethasoneDipropionateBase Beclomethasone Dipropionate 5534-09-8 /Base 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyethanoyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one Beclomethasone,9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione 9-Chloro-16-methylpregna-1,4-diene-11,17,21-triol-3,20-dione Beclomethasone (base and/or unspecified salts) (9-α-Chloro-16-beta-methylprednisolone) (11,16)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 9a-Chloro-16-methylprednisolone Becolvent BecloMethasone Solution 9α-Chloro-16β-Methylprednisolone Beclomethasone - 95% min Beclomethasone - 98% min 9-Chloro-11beta,17,21-trihydroxy-16 omethasone Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11β,16β)- Beclomethasone in Methanol BECLOMETHASONE USP/EP/BP Pregna-1,4-diene-3,20-dione,9-chloro-11,17,21-trihydroxy-16-methyl-, (11b,16b)- Beclometasone (Beclometasone) Beclometasone BecL 9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (Beclometasone) Beclometasone Dipropionate Imp. G (EP) 1, 4-PREGNADIEN-9α-CHLORO-16β-METHYL-11β, 17α, 21-TRIOL-3, 20-DIONE 4419-39-0 2092-13-4 C22H29ClO5 Immunomodulators and Antibiotics Immune System Regulation Immune Cell Signaling and Blood BioChemical Cell Biology Cell Signaling and Neuroscience Intermediates & Fine Chemicals Pharmaceuticals Steroids