Propionyl-L-carnitine hydrochloride
- CAS No.
- 119793-66-7
- Chemical Name:
- Propionyl-L-carnitine hydrochloride
- Synonyms
- ST-261;Propionyl-L-carn;Propionyl L-Carnitine;Propionyllevocarnitine;Levocarnitine propionate;PROPIONYL L-CARNITINE HCL;PROPIONYLLEVOCARNITINE HCL;Propionyl-L-carnitine-d3 HCl;L-Propionylcarnitine chloride;Propionyl-L-carnitine HCI(PLC)
- CBNumber:
- CB1338049
- Molecular Formula:
- C10H20ClNO4
- Molecular Weight:
- 253.72
- MOL File:
- 119793-66-7.mol
- Modify Date:
- 2023/9/20 16:43:00
Melting point | 165-167°C |
---|---|
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | Chloroform (Slightly), Water (Slightly) |
form | Solid |
color | White to Off-White |
Stability | Hygroscopic |
CAS DataBase Reference | 119793-66-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
HS Code | 2923.90.0100 | |||||||||
NFPA 704 |
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Propionyl-L-carnitine hydrochloride price More Price(2)
Propionyl-L-carnitine hydrochloride Chemical Properties,Uses,Production
Description
Propionyl-L-carnitine is a naturally occurring carnitine derivative formed by carnitine acetyltransferase during β-oxidation of uneven chain fatty acids. Propionyl-L-carnitine increases the basal release of prostaglandin E2 (PGE2; ) and 6-keto-prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils and increases the basal release of thromboxane B2 (TXB2; ) in non-contaminated cells. It reduces the production of reactive oxygen species (ROS) and decreases the expression of NADPH oxidase 2 (NOX2), NOX4, and ICAM-1 in human umbilical vein endothelial cells (HUVECs). It also increases the rate of revascularization and the hind limb vascular area in a rabbit model of hind limb ischemia when administered at a dose of 10 mg per animal. Propionyl-L-carnitine reduces mitochondrial dysfunction induced by ischemia, preventing mitochondrial calcium overload, and depletion of ATP tissue stores in a rabbit model of ischemia.
Chemical Properties
White Solid
Uses
L-Propionyl carnitine has been shown to improve the heart's mechanical recovery and other metabolic parameters after ischemia-reperfusion.
Propionyl-L-carnitine hydrochloride Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | China | 2989 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |