N-(Hydroxymethyl)phthalimide
- CAS No.
- 118-29-6
- Chemical Name:
- N-(Hydroxymethyl)phthalimide
- Synonyms
- AURORA KA-454;N-(HydroxymethyL;AKOS BBS-00004724;IFLAB-BB F0777-0575;PHTHALIMIDOMETHANOL;N-(Hydroxymethyl)ph;oxymethylphthalimide;Phthalimidylmethanol;N-Methylolphthalimide;Oxymethyl phthalimide
- CBNumber:
- CB1392676
- Molecular Formula:
- C9H7NO3
- Molecular Weight:
- 177.16
- MOL File:
- 118-29-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
Melting point | 147-149 °C (lit.) |
---|---|
Boiling point | 309.06°C (rough estimate) |
Density | 1.3312 (rough estimate) |
refractive index | 1.5200 (estimate) |
storage temp. | Store below +30°C. |
form | Fine Crystalline Powder |
pka | 13.17±0.10(Predicted) |
color | White |
BRN | 140946 |
InChIKey | MNSGOOCAMMSKGI-UHFFFAOYSA-N |
CAS DataBase Reference | 118-29-6(CAS DataBase Reference) |
NIST Chemistry Reference | 1H-isoindole-1,3(2h)-dione, 2-(hydroxymethyl)-(118-29-6) |
EPA Substance Registry System | N-(Hydroxymethyl)phthalimide (118-29-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Safety Statements | 22-24/25 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TI5270000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29251995 | |||||||||
NFPA 704 |
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N-(Hydroxymethyl)phthalimide price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | H41803 | N-(Hydroxymethyl)phthalimide 97% | 118-29-6 | 100G | ₹8205.35 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.14422 | N-(Hydroxymethyl)-phthalimide for synthesis | 118-29-6 | 100G | ₹3760 | 2022-06-14 | Buy |
ALFA India | ALF-B21292-36 | N-(Hydroxymethyl)phthalimide, 97% | 118-29-6 | 500g | ₹16491 | 2022-05-26 | Buy |
ALFA India | ALF-B21292-22 | N-(Hydroxymethyl)phthalimide, 97% | 118-29-6 | 100g | ₹5575 | 2022-05-26 | Buy |
TCI Chemicals (India) | H0648 | N-Hydroxymethylphthalimide | 118-29-6 | 25G | ₹1800 | 2022-05-26 | Buy |
N-(Hydroxymethyl)phthalimide Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
N-(Hydroxymethyl)phthalimide is used as a reactant in the synthesis of 5-[(3-aralkyl amido/imidoalkyl)phenyl]-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as antiviral agents.
Definition
ChEBI: A primary alcohol comprising phthalimide carrying an N-hydroxymethyl substituent.
Preparation
To a flask equipped with a mechanical stirrer and condenser is added 511 gm (3.47 moles) of phthalimide, 260 ml of 40% formalin (3.47 moles), and 1750 ml of water. The mixture is refluxed for about 5-10 min or until a clear solution results (if any insoluble material remains, it is first filtered). Then the mixture is cooled for several hours. The resulting product is filtered with suction, washed with cold water, and air-dried to afford 594 gm (96%), m.p. 137-141°C.
NOTE: The product should not be oven-dried since it decomposes with the loss of formaldehyde. Recrystallization of the product from ethanol affords 94% recovery of the original material with the same melting point range.
N-(Hydroxymethyl)phthalimide Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Bhakti Impex | +919822268653 | Pune, India | 76 | 58 | Inquiry |
Supra Group of Companies | +91-265-2780165 +91-2652780165 | Gujarat, India | 57 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
Explicit Chemicals Pvt Ltd | +919822268653 | Maharashtra, India | 10 | 58 | Inquiry |
Neuchatel Chemie Specialties | 08066085788Ext 642 | Mumbai, India | 54 | 58 | Inquiry |
Explicit Chemicals Private Limited | 08048972289 | Pune, India | 16 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | 91-79-26462688 | Gujarat, India | 987 | 58 | Inquiry |
Suyara Inds. Pvt. Ltd. | 91-20-25511052 | Maharashtra, India | 33 | 58 | Inquiry |
Hritik Chemical Corporation | +91-22-6692 5779 | Mumbai, India | 55 | 58 | Inquiry |
Hritik Chemicals Pvt., Ltd. | 91-22-26313359 | Maharashtra, India | 88 | 58 | Inquiry |