N-Hydroxyphthalimide
![N-Hydroxyphthalimide Structure](CAS/GIF/524-38-9.gif)
- CAS No.
- 524-38-9
- Chemical Name:
- N-Hydroxyphthalimide
- Synonyms
- nhpi;2-hydroxyisoindoline-1,3-dione;hydroxyphthalimide;2-hydroxyisoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-hydroxy-;HOPHT;H-HYDROXY PHTHALIMIDE;2-Hydroxy-1H-isoindole-1,3(2H)-dione;2-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione;f802
- CBNumber:
- CB2332640
- Molecular Formula:
- C8H5NO3
- Molecular Weight:
- 163.13
- MOL File:
- 524-38-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/24 19:19:26
Melting point | 233 °C (dec.) (lit.) |
---|---|
Boiling point | 290.19°C (rough estimate) |
Density | 1.64 g/cm3 |
vapor pressure | 0Pa at 25℃ |
refractive index | 1.5510 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 6.10±0.20(Predicted) |
form | Powder |
color | Yellow |
Water Solubility | Slightly soluble in water. |
Merck | 14,4838 |
BRN | 131208 |
InChIKey | CFMZSMGAMPBRBE-UHFFFAOYSA-N |
LogP | 0.14 |
CAS DataBase Reference | 524-38-9(CAS DataBase Reference) |
EPA Substance Registry System | 1H-Isoindole-1,3(2H)-dione, 2-hydroxy- (524-38-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H335-H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TI5200000 | |||||||||
TSCA | Yes | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29251995 | |||||||||
NFPA 704 |
|
N-Hydroxyphthalimide price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | H53704 | N-Hydroxyphthalimide 97% | 524-38-9 | 5G | ₹2262.43 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H53704 | N-Hydroxyphthalimide 97% | 524-38-9 | 100G | ₹2749.55 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H53704 | N-Hydroxyphthalimide 97% | 524-38-9 | 500G | ₹7761.53 | 2022-06-14 | Buy |
TCI Chemicals (India) | H0395 | N-Hydroxyphthalimide | 524-38-9 | 25G | ₹1700 | 2022-05-26 | Buy |
TCI Chemicals (India) | H0395 | N-Hydroxyphthalimide | 524-38-9 | 100G | ₹3700 | 2022-05-26 | Buy |
N-Hydroxyphthalimide Chemical Properties,Uses,Production
Chemical Properties
N-Hydroxyphthalimide is yellow moist powder
Uses
N-Hydroxyphthalimide,additives in to DCC method of peptide synthesis used to improve yield of optically pure product.
Application
N-Hydroxyphthalimide is used in the synthesis of a new class of antibacterials potent against macrolide resistant bacteria. Also used in the synthesis of pyrazolidines, isoxazolidines and tetrahydrooxazines.
Purification Methods
N -Hydroxyphthalimide [524-38-9] M 163.1, m 230o, ~235o(dec), 237-240o, 7.0. Dissolve the imide in H2O by adding Et3N to form the salt and while hot, acidify, cool and pour into a large volume of H2O. Filter off the solid, wash it with H2O and dry it over P2O5 in a vacuum. [Nefken & Teser J Am Chem Soc 83 1263 1961, Fieser 1 485 1976, Nefkens et al. Recl Trav Chim, Pays-Bas 81 683 1962] The O-acetyl derivative has m 178-180o (from EtOH). [Beilstein 21/11 V 100.]
N-Hydroxyphthalimide Preparation Products And Raw materials
Raw materials
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chevron_rightSupplier | Tel | Country | ProdList | Advantage | Inquiry |
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Bhakti Impex | +919822268653 | Pune, India | 76 | 58 | Inquiry |
Sam Research Labs | +91 9873930190 | Hyderabad, India | 219 | 58 | Inquiry |
ANJI BIOSCIENCES | +91-9000100077 +91-9000100077 | Hyderabad, India | 430 | 58 | Inquiry |
HEMANT BIOSCIENCE | 9848655224 | Telangana, India | 40 | 58 | Inquiry |
Vihita Chem Private Limited | +91-9512002673 +91-9512002673 | Gujarat, India | 122 | 58 | Inquiry |
TRC FINE CHEMS | +91-7400278327 +91-8097105248 | Mumbai, India | 73 | 58 | Inquiry |
LAASYA LABORATORIES | +91-9573171811 +91-9573171811 | Telangana, India | 9 | 58 | Inquiry |
Shiv Enterprise | +91-9822612471 +91-9822612471 | Maharashtra, India | 10 | 58 | Inquiry |
SYNGENESIS CHEMSCIENCE PRIVATE LIMITED | +91-9067779401 +91-9067779401 | Maharashtra, India | 58 | 58 | Inquiry |
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Bhakti Impex | 58 |
Sam Research Labs | 58 |
ANJI BIOSCIENCES | 58 |
HEMANT BIOSCIENCE | 58 |
Vihita Chem Private Limited | 58 |
TRC FINE CHEMS | 58 |
LAASYA LABORATORIES | 58 |
Shiv Enterprise | 58 |
SYNGENESIS CHEMSCIENCE PRIVATE LIMITED | 58 |
JSK Chemicals | 58 |
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