N-Isopropylacrylamide

N-Isopropylacrylamide Structure
CAS No.
2210-25-5
Chemical Name:
N-Isopropylacrylamide
Synonyms
NIPAM;NIPAAm;acryL;Isopropyl acrylamide;N-isopropylacrylamide ,99%;N-(1-methylethyl)-2-Propenamide;FITC-PEG;AKOS 91289;N-IsopropyL;polyNIPAM-BA
CBNumber:
CB1494912
Molecular Formula:
C6H11NO
Molecular Weight:
113.16
MOL File:
2210-25-5.mol
MSDS File:
SDS
Modify Date:
2024/6/11 18:14:38

N-Isopropylacrylamide Properties

Melting point 60-63 °C(lit.)
Boiling point 89-92 °C2 mm Hg(lit.)
Density 1.0223 (rough estimate)
refractive index 1.4210 (estimate)
storage temp. 2-8°C
pka 14.83±0.46(Predicted)
form Crystalline Powder or Crystals
color White to light yellow
PH pH(50g/l, 25℃) : 7.8~10.0
Water Solubility Slightly soluble in water.
InChIKey QNILTEGFHQSKFF-UHFFFAOYSA-N
LogP 0.278 (est)
CAS DataBase Reference 2210-25-5(CAS DataBase Reference)
NIST Chemistry Reference Acrylamide, n-isopropyl-(2210-25-5)
EPA Substance Registry System 2-Propenamide, N-(1-methylethyl)- (2210-25-5)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P501
Hazard Codes  Xn
Risk Statements  22-36-36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
RTECS  AS3675000
TSCA  Yes
HS Code  29241990
NFPA 704
1
2 1

N-Isopropylacrylamide price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 731129 N-Isopropylacrylamide ≥99% 2210-25-5 5G ₹5444.98 2022-06-14 Buy
Sigma-Aldrich(India) 731129 N-Isopropylacrylamide ≥99% 2210-25-5 25G ₹18110.23 2022-06-14 Buy
Sigma-Aldrich(India) 415324 N-Isopropylacrylamide 97% 2210-25-5 10G ₹5400 2022-06-14 Buy
Sigma-Aldrich(India) 415324 N-Isopropylacrylamide 97% 2210-25-5 50G ₹17660 2022-06-14 Buy
TCI Chemicals (India) I0401 N-Isopropylacrylamide (stabilized with MEHQ) min. 98.0 % 2210-25-5 25G ₹5200 2022-05-26 Buy
Product number Packaging Price Buy
731129 5G ₹5444.98 Buy
731129 25G ₹18110.23 Buy
415324 10G ₹5400 Buy
415324 50G ₹17660 Buy
I0401 25G ₹5200 Buy

N-Isopropylacrylamide Chemical Properties,Uses,Production

Description

N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).

Chemical Properties

white to light yellow crystalline powder or

Uses

Binders in textiles, paper, adhesives, detergents, cosmetics.
N-Isopropylacrylamide is used to produce poly(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA or pNIPAm) thermo sensitive polymer- or copolymer-based hydrogels. Polymers that contain NIPAM shrink dramatically above 33°C. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.

Application

N-Isopropylacrylamide (NIPAM) can be used to prepare poly(NIPAM) based thermosetting polymers, which can be used for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.
Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.

General Description

N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties. These properties include temperature based volumetric and phase changes, which change when the temperature of the solution reaches a lower critical solution temperature (LCST).

Purification Methods

Fractionate the amide under reduced pressure, and recrystallise the solid distillate from hexane (m 59o), *C6H6 (m 62o) or *C6H6/hexane (m 62-63o). Store it with 0.05% of 4-tert-butylcatechol. It is used for making water soluble swellable hydrogels. [Beilstein 4 IV 517.]

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N-Isopropylacrylamide ,99% [stabilized] -PropenaMide, N-(1-Methylethyl)- N-IsopropylacrylaMide  N-IsopropylacrylaMide, stabilized, pure, 99% 100GR N-IsopropylacrylaMide, stabilized, pure, 99% 500GR polyNIPAM-BA N-IsopropylacrylaMide, 99%, stabilized with 500 ppM MEHQ N-IsopropylacrylaMide, stabilized with 500 ppM MEHQ AKOS 91289 ISOPROPYLACRYLAMIDE(N-) N-ISOPROPYLACRYLAMIDE 2-Propenamide, N-(1-methylethyl)- Isopropylamid kyseliny akrylove isopropylamidkyselinyakrylove n-(1-methylethyl)-2-propenamid Acrylamide, N-isopropyl. N-Isopropylacrylamide ,99% [pure,stabilized] N-ISOPROPYLACRYLAMIDE, 99%, STABILIZED, PURE N-Isopropylacrylamide, stabilized, pure, 99% n-isopropylacrylamide ,98% [pure,stabilized] n-isopropyl-acrylamid N-IsopropyL N-Isopropylacrylamide, 98%, stabilized with 500 ppm MEHQ N-Isopropylacrylamide (stabilized with MEHQ)> N-Isopropylacrylamide, 99%, reagent grade, stabilized with 500 ppm MEHQ N-Isopropylacrylamide (NIPAM) N-IsopropylacrylaMide -PropenaMide N-Isopropylacrylamide (NIPAM) extrapure, 99% N-isopropylacrylamide ,99% Isopropyl acrylamide NIPAM NIPAAm N-(1-methylethyl)-2-Propenamide acryL FITC-PEG N-Isopropylacrylamide (sabilized wih MEHQ), 98% Alflutinib Impurity 7 N-lsopropylacrylamide 2210-25-5 H2CCHCONHCHCH32 AMINE Acrylamide and Methacrylamide Acrylic Monomers Monomers