N-Isopropylacrylamide
![N-Isopropylacrylamide Structure](CAS/GIF/2210-25-5.gif)
- CAS No.
- 2210-25-5
- Chemical Name:
- N-Isopropylacrylamide
- Synonyms
- NIPAM;NIPAAm;acryL;Isopropyl acrylamide;N-isopropylacrylamide ,99%;N-(1-methylethyl)-2-Propenamide;FITC-PEG;AKOS 91289;N-IsopropyL;polyNIPAM-BA
- CBNumber:
- CB1494912
- Molecular Formula:
- C6H11NO
- Molecular Weight:
- 113.16
- MOL File:
- 2210-25-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/11 18:14:38
Melting point | 60-63 °C(lit.) |
---|---|
Boiling point | 89-92 °C2 mm Hg(lit.) |
Density | 1.0223 (rough estimate) |
refractive index | 1.4210 (estimate) |
storage temp. | 2-8°C |
pka | 14.83±0.46(Predicted) |
form | Crystalline Powder or Crystals |
color | White to light yellow |
PH | pH(50g/l, 25℃) : 7.8~10.0 |
Water Solubility | Slightly soluble in water. |
InChIKey | QNILTEGFHQSKFF-UHFFFAOYSA-N |
LogP | 0.278 (est) |
CAS DataBase Reference | 2210-25-5(CAS DataBase Reference) |
NIST Chemistry Reference | Acrylamide, n-isopropyl-(2210-25-5) |
EPA Substance Registry System | 2-Propenamide, N-(1-methylethyl)- (2210-25-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H302-H318 | |||||||||
Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P501 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-36-36/37/38 | |||||||||
Safety Statements | 26-36/37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | AS3675000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29241990 | |||||||||
NFPA 704 |
|
N-Isopropylacrylamide price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 731129 | N-Isopropylacrylamide ≥99% | 2210-25-5 | 5G | ₹5444.98 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 731129 | N-Isopropylacrylamide ≥99% | 2210-25-5 | 25G | ₹18110.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 415324 | N-Isopropylacrylamide 97% | 2210-25-5 | 10G | ₹5400 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 415324 | N-Isopropylacrylamide 97% | 2210-25-5 | 50G | ₹17660 | 2022-06-14 | Buy |
TCI Chemicals (India) | I0401 | N-Isopropylacrylamide (stabilized with MEHQ) min. 98.0 % | 2210-25-5 | 25G | ₹5200 | 2022-05-26 | Buy |
N-Isopropylacrylamide Chemical Properties,Uses,Production
Description
N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).
Chemical Properties
white to light yellow crystalline powder or
Uses
Binders in textiles, paper, adhesives, detergents, cosmetics.
N-Isopropylacrylamide is used to produce poly(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA or pNIPAm) thermo sensitive polymer- or copolymer-based hydrogels. Polymers that contain NIPAM shrink dramatically above 33°C. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.
Application
N-Isopropylacrylamide (NIPAM) can be used to prepare poly(NIPAM) based thermosetting polymers, which can be used for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.
Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.
General Description
N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties. These properties include temperature based volumetric and phase changes, which change when the temperature of the solution reaches a lower critical solution temperature (LCST).
Purification Methods
Fractionate the amide under reduced pressure, and recrystallise the solid distillate from hexane (m 59o), *C6H6 (m 62o) or *C6H6/hexane (m 62-63o). Store it with 0.05% of 4-tert-butylcatechol. It is used for making water soluble swellable hydrogels. [Beilstein 4 IV 517.]
N-Isopropylacrylamide Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
anjali labs | +91-9763681015 +91-9860682220 | Maharashtra, India | 19 | 58 | Inquiry |
Jigs chemical | +91 (79) 26402695/26401498 | Gujarat, India | 319 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Chaturya Biotech (Tanuj Life Sciences) | 91-7702707258 | Hyderabad, India | 399 | 58 | Inquiry |
Angene Chemical Private Limited | 91-40-48515518 | Hyderabad, India | 68 | 58 | Inquiry |
Anjali Labs | 08068441127Ext 140 | Maharashtra, India | 14 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
Supplier | Advantage |
---|---|
GLR Innovations | 58 |
anjali labs | 58 |
Jigs chemical | 58 |
Triveni chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Sisco Research Laboratories Pvt. Ltd. | 58 |
Chaturya Biotech (Tanuj Life Sciences) | 58 |
Angene Chemical Private Limited | 58 |
Anjali Labs | 58 |
Clearsynth Labs | 58 |
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