ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Thyroid hormone and antithyroid drugs >Thyrotropin-releasing hormone

Thyrotropin-releasing hormone

Thyrotropin-releasing hormone Structure
CAS No.
24305-27-9
Chemical Name:
Thyrotropin-releasing hormone
Synonyms
PROTIRELIN;PIN2;TRF;THYROTROPIN RELEASING HORMONE;TRH (Thyrotropin Releasing Hormone);TRH;Prem;TRF1;TRBF1;TERF1
CBNumber:
CB1408948
Molecular Formula:
C16H22N6O4
Molecular Weight:
362.38
MOL File:
24305-27-9.mol
MSDS File:
SDS
Modify Date:
2024/8/21 22:41:43

Thyrotropin-releasing hormone Properties

Melting point >143°C (dec.)
alpha -50 (D/25℃) (c=1.5, H2O)-65.5 (D) (c=1.0, H2O)
Boiling point 494°C (rough estimate)
Density 1.1675 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. −20°C
solubility H2O: 10 mg/mL, clear, colorless
pka 13.05±0.20(Predicted)
form powder
color White to Off-White
PH pH (10g/l, 25℃) : 3.0~4.0
Merck 13,9663
BRN 770238
Stability Hygroscopic
InChIKey ITYONPBTNRIEBA-SRVKXCTJSA-N
CAS DataBase Reference 24305-27-9

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  2
RTECS  TW3580000
10-21
NFPA 704
0
3 0

Thyrotropin-releasing hormone price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P1319 Thyrotropin releasing hormone ≥98% (HPLC), powder 24305-27-9 50MG ₹14061.68 2022-06-14 Buy
Sigma-Aldrich(India) SAB4502943 Anti-Telomeric Repeat Binding Factor 1 antibody produced in rabbit affinity isolated antibody 24305-27-9 100μG ₹50560.5 2022-06-14 Buy
Sigma-Aldrich(India) P1319 Thyrotropin releasing hormone ≥98% (HPLC), powder 24305-27-9 250MG ₹51808.45 2022-06-14 Buy
Sigma-Aldrich(India) SAB1305990 ANTI-TRF (TERF1)(C-TERMINAL) antibody produced in rabbit purified immunoglobulin, buffered aqueous solution 24305-27-9 400μL ₹47796.6 2022-06-14 Buy
Sigma-Aldrich(India) P1319 Thyrotropin releasing hormone ≥98% (HPLC), powder 24305-27-9 1G ₹174747.98 2022-06-14 Buy
Product number Packaging Price Buy
P1319 50MG ₹14061.68 Buy
SAB4502943 100μG ₹50560.5 Buy
P1319 250MG ₹51808.45 Buy
SAB1305990 400μL ₹47796.6 Buy
P1319 1G ₹174747.98 Buy

Thyrotropin-releasing hormone Chemical Properties,Uses,Production

Chemical Properties

White or yellowish-white powder, hygroscopic.

Uses

prothyrotropin

Indications

Thyrotropin-releasing hormone, or protirelin, consists of three amino acids. TRH (Relefact TRH) is used for tests to distinguish primary from secondary hypothyroidism.

General Description

Thyrotropin releasing hormone (TRH) is a tripeptide hypothalamic regulatory hormone, encoded by the gene mapped to human chromosome 3q13.3-q21. TRH is expressed in a variety of organs including central nervous system (CNS) and gastrointestinal tract.

Side effects

The peak TSH response to intravenous TRH occurs at 20 minutes. The mild and transient side effects, which occur only after intravenous TRH, include nausea, a flushing sensation, a desire to micturate, a peculiar taste, and tightness in the chest[1].

Thyrotropin-releasing hormone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 268)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-81148696 +86-15536356810 China 3878 58 Inquiry
Hebei Yanxi Chemical Co., Ltd. +86-17531190177; +8617531190177 China 5873 58 Inquiry
Dorne Chemical Technology co. LTD +86-86-13583358881 +8618560316533 China 3144 58 Inquiry
Shanghai Yunao International Trade Co., Ltd +8617621705551 China 265 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10991 58 Inquiry
Nantong Guangyuan Chemicl Co,Ltd +undefined17712220823 China 616 58 Inquiry
Hebei Weimiao Import and Export Trade Co., Ltd. +undefined19948166995 China 73 58 Inquiry
hebei hongtan Biotechnology Co., Ltd +86-86-1913198-3935 +8617331935328 China 973 58 Inquiry

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