ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Thyroid hormone and antithyroid drugs >Thyrotropin-releasing hormone
Thyrotropin-releasing hormone
![Thyrotropin-releasing hormone Structure](CAS/GIF/24305-27-9.gif)
- CAS No.
- 24305-27-9
- Chemical Name:
- Thyrotropin-releasing hormone
- Synonyms
- PROTIRELIN;PIN2;TRF;THYROTROPIN RELEASING HORMONE;TRH (Thyrotropin Releasing Hormone);TRH;Prem;TRF1;TRBF1;TERF1
- CBNumber:
- CB1408948
- Molecular Formula:
- C16H22N6O4
- Molecular Weight:
- 362.38
- MOL File:
- 24305-27-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
Melting point | >143°C (dec.) |
---|---|
alpha | -50 (D/25℃) (c=1.5, H2O)-65.5 (D) (c=1.0, H2O) |
Boiling point | 494°C (rough estimate) |
Density | 1.1675 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | −20°C |
solubility | H2O: 10 mg/mL, clear, colorless |
pka | 13.05±0.20(Predicted) |
form | powder |
color | White to Off-White |
PH | pH (10g/l, 25℃) : 3.0~4.0 |
Merck | 13,9663 |
BRN | 770238 |
Stability | Hygroscopic |
InChIKey | ITYONPBTNRIEBA-SRVKXCTJSA-N |
CAS DataBase Reference | 24305-27-9 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Safety Statements | 22-24/25 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | TW3580000 | |||||||||
F | 10-21 | |||||||||
NFPA 704 |
|
Thyrotropin-releasing hormone price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P1319 | Thyrotropin releasing hormone ≥98% (HPLC), powder | 24305-27-9 | 50MG | ₹14061.68 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SAB4502943 | Anti-Telomeric Repeat Binding Factor 1 antibody produced in rabbit affinity isolated antibody | 24305-27-9 | 100μG | ₹50560.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P1319 | Thyrotropin releasing hormone ≥98% (HPLC), powder | 24305-27-9 | 250MG | ₹51808.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SAB1305990 | ANTI-TRF (TERF1)(C-TERMINAL) antibody produced in rabbit purified immunoglobulin, buffered aqueous solution | 24305-27-9 | 400μL | ₹47796.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P1319 | Thyrotropin releasing hormone ≥98% (HPLC), powder | 24305-27-9 | 1G | ₹174747.98 | 2022-06-14 | Buy |
Thyrotropin-releasing hormone Chemical Properties,Uses,Production
Chemical Properties
White or yellowish-white powder, hygroscopic.
Uses
prothyrotropin
Indications
Thyrotropin-releasing hormone, or protirelin, consists of three amino acids. TRH (Relefact TRH) is used for tests to distinguish primary from secondary hypothyroidism.
General Description
Thyrotropin releasing hormone (TRH) is a tripeptide hypothalamic regulatory hormone, encoded by the gene mapped to human chromosome 3q13.3-q21. TRH is expressed in a variety of organs including central nervous system (CNS) and gastrointestinal tract.
Side effects
The peak TSH response to intravenous TRH occurs at 20 minutes. The mild and transient side effects, which occur only after intravenous TRH, include nausea, a flushing sensation, a desire to micturate, a peculiar taste, and tightness in the chest[1].
Thyrotropin-releasing hormone Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 268)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | China | 3878 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5873 | 58 | Inquiry |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | China | 3144 | 58 | Inquiry |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 | China | 265 | 58 | Inquiry |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | China | 10991 | 58 | Inquiry |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | China | 616 | 58 | Inquiry |
Hebei Weimiao Import and Export Trade Co., Ltd. | +undefined19948166995 | China | 73 | 58 | Inquiry |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | China | 973 | 58 | Inquiry |
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- TRH promotes thyroid-stimulating hormone release and can be used in the treatment of depression.
- Sep 6,2023
24305-27-9(Thyrotropin-releasing hormone)Related Search:
synthetictsh-releasinghormone
THYROTROPIN RELEASING HORMONE ACETATE TE
PGLU-HIS-PRO AMIDE ACETATE F & D VERSIO
GLP-HIS-PRO-NH2
H-PGLU-HIS-PRO-NH2
L-PYROGLUTAMYL-L-HISTIDYL-L-PROLINAMIDE
THYROLIBERIN
THYROTROPIN RELEASING HORMONE 1-2
THYROTROPIN RELEASING HORMONE 2-3
THYROTROPIC RELEASING HORMONE
THYROTROPIN RELEASING HORMONE, HUMAN
THYROTROPIN RELEASING HORMONE (HUMAN, OVINE, PORCINE, RAT)
Thyrotropic hormone-releasing hormone
Thyrotropin-releasing factor (8CI)
PROTIRELIN PH. EUR.
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxo-propan-2-yl]-5-oxo-pyrrolidine-2-carboxamide
(Pyro)-L-glutamic acid-L-histidine-L-proline-NH2
Abbott 38579
L-Prolinamide, 5-oxo-L-prolyl-L-histidyl- (9CI)
Prem
Relefact TRH
Rifotironin
Stimu TSH
Synthetic thyrotropin-releasing factor
Synthetic thyrotropin-releasing hormone
Thypinone
Thyrefact
Thyroid-stimulating hormone-releasing factor
Thyrotropic hormone-releasing factor
4,5-DIAMINO-6-HYDROXY-2-PYRIMIDINETHIOL HEMISULFATE-1,5-HYDRATE
TRH
TRH, HUMAN
TRH (HUMAN, OVINE, PORCINE, RAT)
THR 1-2
THR 2-3
PYROGLU-HIS-PRO AMIDE
PYROGLU-HIS-PRO NH2
PYR-HIS-PRO-NH2(TRH)
PYR-HIS-PRO-NH2
PGLU-HIS-PRO-NH2
PGLU-HIS-PRO AMIDE
5-oxo-l-prolyl-l-histidyl-l-prolinamid
fda1725
lopremone
(2S)-N-[(2S)-1-[(2S)-2-Carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-2-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
GLP-HIS-PRO-NH2: GLP-HP-NH2
Pyr-HP-NH2
hTRF1-AS
Monoclonal Anti-TERF1 antibody produced in mouse
TRF1
t-TRF1
ANTI-TRF (TERF1)(C-TERMINAL) antibody produced in rabbit
TRBF1
Anti-Telomeric Repeat Binding Factor 1 antibody produced in rabbit
NIMA-interacting protein 2
TERF1
TTAGGG repeat binding factor 1
thyroidreleasinghormone