Naloxone hydrochloride
- CAS No.
- 357-08-4
- Chemical Name:
- Naloxone hydrochloride
- Synonyms
- NALOXONE HCL;narcan;en1530;Nalone;nalonee;nih7890;EN-15304;Narcanti;Naloxone hydrochlori;NALOXONE HYDROCHLORIDE
- CBNumber:
- CB1409273
- Molecular Formula:
- C19H22ClNO4
- Molecular Weight:
- 363.84
- MOL File:
- 357-08-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/24 22:20:23
| Melting point | 200-2050C |
|---|---|
| RTECS | QD2275000 |
| storage temp. | 2-8°C |
| solubility | ethanol: 3.3 mg/mL stable for several months refrigerated if protected from light. |
| form | powder |
| color | white to off-white |
| Water Solubility | Soluble in water (73 mg/ml), ethanol (3.3 mg/ml), methanol (50 mg/ml) and dimethyl sulfoxide (73 mg/ml). Insoluble in ether |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months. |
| CAS DataBase Reference | 357-08-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-26-36/37/39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
Naloxone hydrochloride Chemical Properties,Uses,Production
Description
Naloxone (hydrochloride) (CRM) (Item No. ISO60191) is a certified reference material categorized as an opioid antagonist. Formulations containing naloxone have been used as antidotes for opioid overdose and the prevention of overdose. They have also been used in combination with buprenorphine (Item Nos. ISO60178 | 14025) in the treatment of opiate addiction and in pain management. This product is intended for research and forensic applications.
Chemical Properties
Crystalline Solid
Uses
Naloxone Hydrochloride is a specific opioid antagonist. Narcotic antagonist.
Definition
ChEBI: A hydrochloride resulting from the formal reaction of equimolar amounts of naloxone and hydrogen chloride. A specific opioid antagonist, it is used to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known r suspected opioid overdose.
Biological Activity
Opioid antagonist.
Naloxone hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 256)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Micro Orgo Chem | +91-91-022-24969510 +91-9082984052 | Mumbai, India | 66 | 58 | Inquiry |
| RESONANCE LABS | +91-8027630180 +91-8027630180 | Karnataka, India | 32 | 58 | Inquiry |
| R L Fine Chem Pvt. Ltd | +91-8042488999 +91-8042488999 | Karnataka, India | 74 | 58 | Inquiry |
| Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Rusan Pharma Ltd | +91-2228687035 +91-9690022465 | Maharashtra, India | 14 | 58 | Inquiry |
| Micron Pharmaceuticals | 91-22-24969511 | Maharashtra, India | 43 | 58 | Inquiry |
| Deccan Nutraceuticals Pvt. Ltd | +91-9822641298 +91-9822641298 | Mumbai, India | 18 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Jigs Chemical ltd | 58 |
| Micro Orgo Chem | 58 |
| RESONANCE LABS | 58 |
| R L Fine Chem Pvt. Ltd | 58 |
| Sun Pharmaceutical Industries Ltd | 58 |
| Ralington Pharma | 58 |
| Rusan Pharma Ltd | 58 |
| Micron Pharmaceuticals | 58 |
| Deccan Nutraceuticals Pvt. Ltd | 58 |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
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NALOXONE HYDROCHLORIDE
(5ALPHA)-4,5-EPOXY-3,14-DIHYDRO-17-(2-PROPENYL)MORPHINAN-6-ONE HYDROCHLORIDE
17-allyl-4,5-alpha-epoxy-3,14-dihydroxymorphinan-6-onehydrochloride
4,5alpha-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride
en1530
l-n-allyl-14-hydroxynordihydromorphinonehydrochloride
morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-,hydrochloride,(5-a
nalonee
17-allyl-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-onhydrochloride
(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)Morphinan-6-one Hydrochloride
17-Allyl-4,5α-epoxy-3,14-dihydroxyMorphinan-6-one Hydrochloride
Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5a)-
17-Allyl-3,14-dihydroxy-4,5alpha-epoxyMorphinan-6-one hydrochloride
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5α)-
nih7890
(5alpha)-17-allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
NALOXONE HYDROCHLORIDE OPIOID ANTAGONIST
NALOXONE HYDROCHLORIDE CRYSTALLINE
(5a)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one Hydrochloride
17-Allyl-4,5a-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride
EN-15304
Nalone
Narcanti
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5.alpha.)-
(-)-N-Allyl-14-hydroxynordihydromorphinone hydrochloride
l-Naloxone hydrochloride
Morphinan-6-one, 17-allyl-4,5a-epoxy-3,14-dihydroxy-, hydrochloride (8CI)
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5a)- (9CI)
N-Allyldihydro-14-hydroxynormorphinone hydrochloride
Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, hydrochloride (7CI)
(5alpha)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride
(5α)-4,5-Epoxy-3,14-dihydro-17-(2-propenyl)morphinan-6-onehydrochloride
Naloxone hydrochloride (controlled)
Naloxone (hydrochloride) (CRM)
Naloxone hydrochloride USP/EP/BP
Naloxone hydrochlori
NALOXONE HCL
narcan
Naloxone Hydrochloride hydrate
357-08-4
C19H21NO4HClH2O
C19H21NO4HCl
C19H22ClNO4
C19H21NO4HClC19H22ClNO4
API
Chiral Reagents
Drug Analogues
Intermediates & Fine Chemicals
Pharmaceuticals
Opioid receptor and opioid-like receptor
Opioids