(6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester

(6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester Structure
CAS No.
54639-48-4
Chemical Name:
(6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester
Synonyms
3-Oh;GHYH;3-hydroxycephem;3-OH(GOH);3- hydroxy group;3-hydroxy cephalosporin;Trihydroxycephalosporin;Ceftizoxime Impurity 43;Ceftizoxime Impurity 67;Three in latiravir potassium
CBNumber:
CB1495818
Molecular Formula:
C28H24N2O5S
Molecular Weight:
500.57
MOL File:
54639-48-4.mol
MSDS File:
SDS
Modify Date:
2024/4/26 14:50:00

(6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester Properties

Boiling point 777.1±60.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 4.50±1.00(Predicted)
CAS DataBase Reference 54639-48-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330

(6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester Chemical Properties,Uses,Production

Uses

3(6R,7R)--Hydroxy-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Diphenylmethyl Ester is a useful synthetic intermediate. It was used to prepare cephalosporin-derived inhibitors. It can also be used to synthesize Ceftaroline Fosamil which is a cephalosporin antibiotic.

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(6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester Spectrum

GHYH (7-PHENYLACETAMIDE-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACIDDIPHENYLMETHYL ESTER) (6R,7R)-Benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-ca Benzhydryl (6R,7R)-3-hydroxy-8-oxo-7-[(2-phenylacetyl)aMino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (6R,7R)-Benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetaMido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 3-hydroxy cephalosporin 7-Phenyl acetylamino-3-hydroxy-3-cephemcyclo-4- carboxylic acid diphenyl methyl ester(3-OH) 7-Phenylacetamide-3-Hydroxy-3-cephem-4- 3- hydroxy group (6R,7R)-Benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2 7-PHENYL ACETAMIDO-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACID DIPHENYLMETHYL ESTER 7-PHENYLACETAMIDE-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACID DIPHENYLMETHYL ESTER 3-hydroxy-8-oxo-7-[(phenylacetyl)amino]-,diphenylmethylester,(6R,7R)-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 3-hydroxy-8-oxo-7-[(phenylacetyl)amino]-, diphenylmethyl ester, (6R,7R)-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-hydroxy-8-oxo-7-[(phenylacetyl)amino]-,diphenylmethyl ester,(6R,7R)- (6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl ester 3-OH: 7-PHENYL ACETAMIDO-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACID DIPHENYLMETHYL ESTER 3-OH(GOH) 7-PHENYL ACETAMIDO-3-HYDROXY-3-CEPHEM-4-CARBOXYLIC ACID DIPHENYLMETHYL ESTER , 3-OH 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-hydroxy-8-oxo-7-[(2-phenylacetyl)amino]-, diphenylmethyl ester,(6R,7R)-EINECS 6R,7R)-Benzhydryl3-hydroxy-8-oxo-7-(2-phenylacetamido) -5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylate 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-hydroxy-8-o 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-hydroxy-8-oxo-7-[(phenylacetyl)amino]-, diphenylmethyl ester, (6R,7R)-(9CI) (6r,7r)-3-hydroxy-8-oxo-7-((phenylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid diphenyl methyl (6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenyl methyl esterChemicalBook 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-hydroxy-8-oxo-7-[(2-phenylacetyl)amino]-, diphenylmethyl ester, (6R,7R)- Trihydroxycephalosporin Three in latiravir potassium 7-PHENYL ACETAMIDO-3-HYDROXY-3-CEPHEM-4-CARBOXYLTC ACID DIPHENYLMETHYL ESTER 7-Phenylacetamide-3-Hydroxy-3-cephem-4-carboxylic acid diphe... 3- Hydroxycephalosporin Intermediate of Ceftizoxime Sodium GHYH 3-Oh 3-hydroxycephem Benzhydryl (6R,7R)-3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]Oct-2-ene-2-carboxylate Diphenylmethyl (6R,7R)-3-hydroxy-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (3-OH) 7-Phenyl acetylamino-3-hydroxy-3-cephemcyclo-4-carboxylic acid diphenyl methyl ester Ceftizoxime Impurity 43 Ceftizoxime Impurity 67 3(6R,7R)-Hydroxy-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ac (6R,7R)-3-Hydroxy-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic 54639-48-4 C28H24N2O5S Organic acids