CYCLACILLIN (200 MG)
- CAS No.
- 3485-14-1
- Chemical Name:
- CYCLACILLIN (200 MG)
- Synonyms
- wy4508;Calthor;Vipicil;Wyvital;Vatracin;cyclapen;NSC 88789;Citosarin;CICLACILIN;vastcillin
- CBNumber:
- CB1501397
- Molecular Formula:
- C15H23N3O4S
- Molecular Weight:
- 341.43
- MOL File:
- 3485-14-1.mol
- Modify Date:
- 2024/7/10 15:15:42
| Melting point | 182-183° (anhydrate) (Hou, Poole); mp 156-158° (dec) (Alburn et al.) |
|---|---|
| alpha | D25 +268° (water) |
| Boiling point | 649.6±55.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | pK1, pK2 in water: 2.68, 7.50; in 50% dioxane: 4.16, 7.04(at 25℃) |
| color | White to Off-White |
| Water Solubility | 32g/L(25 ºC) |
| Stability | Hygroscopic |
CYCLACILLIN (200 MG) Chemical Properties,Uses,Production
Description
Ciclacillin was synthesized by Wyeth Laboratories in 1967 in the course of studies on the improvement of oral absorption of ampicillin. Although its antibacterial activity is one-sixteenth to one-half that of ampicillin, it shows a four to tenfold higher oral absorption and higher urinary excretion. Ciclacillin shows less tendency than ampicillin to cause diarrhea and is used for therapy of pyoderma, wound infection, respiratory and urinary tract infections, as well as ear and nose, and other infections caused by Staphylococcus, Streptococcus, Escherichia coli, Citrobacter, Klebsiella, Proteus, and Haemophilus influenzae.
Uses
Antibacterial.
Antimicrobial activity
The structure differs from other aminopenicillins in that the benzene ring is completely saturated and the amino substituent is attached directly to it instead of being linked to an adjacent carbon atom. It is less active than ampicillin against staphylococci, streptococci and H. influenzae, but is better absorbed by mouth, peak plasma levels of 10–18 mg/L being reached after a 500 mg oral dose. Its pharmacokinetic properties, side effects and use resemble those of ampicillin. It has limited availability.
CYCLACILLIN (200 MG) Preparation Products And Raw materials
CYCLACILLIN (200 MG) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | China | 3483 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9030 | 58 | Inquiry |
| United States Biological | 800.520.3011 or 781.639.5092 | United States | 6256 | 80 | Inquiry |
| Zhejiang Huida Biotech Co., LTD | 0571-0571-89903882 15990081639 | China | 3705 | 58 | Inquiry |
| Zhejiang Huida Biotech Co., LTD | 0571-89903882 13626641628 | China | 3657 | 58 | Inquiry |
| BOC Sciences | 1-631-485-4226; 16314854226 | United States | 14059 | 65 | Inquiry |
| A.T.CHEMICAL | 0755-86655561 81899190 | China | 6594 | 51 | Inquiry |
| Service Chemical Inc. | 888-895-6920 | Germany | 6373 | 71 | Inquiry |
| Shanghai New Union Textra Import & Export Co., Ltd | +861-348-227-9455 | China | 2752 | 60 | Inquiry |