6-Aminopenicillanic acid
- CAS No.
- 551-16-6
- Chemical Name:
- 6-Aminopenicillanic acid
- Synonyms
- 6-APA;6-amino penicillanic acid(6-APA);6-Amino;Flucloxacillin EP Impurity C;AMoxicillin Related CoMpound A;6-AMINO-2,2-DIMETHYL-5-OXOPERHYDROAZETO[2,1-B][1,3]THIAZOLE-3-CARBOXYLIC ACID;Amoxicillin Related Compound A (15 mg) ((2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid);penin;6-aps;penicin
- CBNumber:
- CB1410046
- Molecular Formula:
- C8H12N2O3S
- Molecular Weight:
- 216.26
- MOL File:
- 551-16-6.mol
- Modify Date:
- 2024/6/24 22:20:23
| Melting point | 198-200 °C (dec.)(lit.) |
|---|---|
| alpha | 276.3 º (c=1.2, 0.1N HCl 22 ºC) |
| Boiling point | 460.2±45.0 °C(Predicted) |
| Density | 1.3418 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | 2-8°C |
| solubility | 2.46g/l |
| form | Fine Powder |
| pka | pKa 2.3 (Uncertain) |
| color | White to cream |
| PH | 3.4 (100g/l, H2O) |
| optical activity | [α]22/D +276.3°, c = 1.2 in 0.1 M HCl |
| Water Solubility | Soluble in water and hydrochoric acid. |
| Merck | 14,458 |
| BRN | 15080 |
| Stability | Light sensitive |
| InChIKey | NGHVIOIJCVXTGV-SDKNWNMFSA-N |
| LogP | -3.87 at 22.5℃ |
| CAS DataBase Reference | 551-16-6(CAS DataBase Reference) |
| EPA Substance Registry System | 6-Aminopenicillanic acid (551-16-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 42/43 | |||||||||
| Safety Statements | 22-36/37-45-37-24-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | XH8225000 | |||||||||
| F | 10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
6-Aminopenicillanic acid price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A70909 | (+)-6-Aminopenicillanic acid 96% | 551-16-6 | 10G | ₹3344.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A70909 | (+)-6-Aminopenicillanic acid 96% | 551-16-6 | 50G | ₹8346.08 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 07307 | (+)-6-Aminopenicillanic acid analytical standard | 551-16-6 | 100MG | ₹6365.1 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A0800 | 6-Aminopenicillanic Acid | 551-16-6 | 5G | ₹2000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A0800 | 6-Aminopenicillanic Acid | 551-16-6 | 25G | ₹3500 | 2022-05-26 | Buy |
6-Aminopenicillanic acid Chemical Properties,Uses,Production
Chemical Properties
WHITE TO CREAM FINE POWDER
Uses
(+)-6-Aminopenicillanic Acid is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins.
Definition
ChEBI: A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and ph rmacologic characteristics.
General Description
Chemical structure: ?-lactam
Safety Profile
Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Purification Methods
This acid crystallises from water. [Kleppe & Stroninger J Biol Chem 254 4856 1979,Beilstein 27 III/IV 2858.]
6-Aminopenicillanic acid Preparation Products And Raw materials
Raw materials
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Global( 521)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMXTREE STANDARDS | +919872732255 | Punjab, India | 96 | 58 | Inquiry |
| OPULENT PHARMA | +91-9106692785 +91-9106692785 | Gujarat, India | 479 | 58 | Inquiry |
| Chemicea Pharmaceuticals Pvt Ltd | +91-918482849343 +91-8482849343 | Mumbai, India | 461 | 58 | Inquiry |
| CLEANCHEM LABORATORIES LLP | +91-9951015911 +91-9951015911 | Mumbai, India | 281 | 58 | Inquiry |
| Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
| MOLECRAFT LIFE SCIENCES PVT LTD | +91 9581188881 | Telangana, India | 189 | 58 | Inquiry |
| Orgamine Chemicals(I) Pvt Ltd | +91-9820080281 +91-9820080281 | Maharashtra, India | 451 | 58 | Inquiry |
| KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
| Ebenezer Industries | Gujarat, India | 96 | 58 | Inquiry | |
| Penam Laboratories Ltd | +91-1145084500 +91-1145084500 | New Delhi, India | 13 | 58 | Inquiry |
551-16-6(6-Aminopenicillanic acid)Related Search:
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6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
(+)-6-AMINOPENICILLANIC ACID
6-AMINOPENICILLANIC ACID
6-AMINO PENICILLINIC ACID
7-AMINO-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID
(25,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
(2S,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO-[3.2.0]HEPTANE-2-CARBOXYLIC ACID
aminopenicillanicacid
penicin
penin
phenacyl6-aminopenicillinate
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-amino-3,3-dimethyl-7-oxo-, [2S-(2alpha,5alpha,6beta)]-
6-Aminopenicillanic acid;6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-APA
6-Aminopenicillanicacid,98%
6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid 98%
6-Aminopenicillansure
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-amino-3,3-dimethyl-7-oxo-,[2S-(2.alpha.,5.alpha.,6.beta.)]
6-AMINOPENICILLANIC ACID 99%
(2S,5R,6R)-6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid 98%
(2S,5R,6R)-6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid
AMoxicillin IMpurity A (SulbactaM IMpurity B)
Piperacillin IMpurity H
Amoxicillin EP Impurity A
(+)-6-Aminopenicillanic acid, >=99.0%
Penicillan intermediate: penicillan core
6-Aminopenicillanic acid for synthesis
(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
6-APA
6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
6-amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1
4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-amino-3,3-dimethyl-7-oxo
5alpha,6beta)]-[2s-(2alpha
6-amino-3,3-dimethyl-7-oxo-,[2S-(2.alpha.,5.alpha.,6.beta.)]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid
6-aps
6-APA, (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-amino-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
(2S,5β)-6α-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid
(2β,5β)-6α-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid
(6R)-6-Aminopenicillanic acid
6-Aminopenicillanic acid,96%
6-AMinopenicillanic acid, 96% 25GR
[2S-(2α,5α,6β)]-6-AMino-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
NSC 50071
4-AMino-5-nitroso-2,6-pyriMidinediol-13C2
5-Nitroso-6-aMinouracil-13C2
6-AMino-5-nitroso-2,4(1H,3H)-pyriMidinedione-13C2
6-AMino-5-nitroso-2,4-pyriMidinediol-13C2
6-AMino-5-nitroso-22,4(1H,3H)-pyriMidinedione-13C2
6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
6-APA
6-amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1
(+)-6-Aminopenicillanic acid,(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-APA
(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (6-Aminopenicillanic Acid)
SulbactaM IMpurity B (AMoxicillin IMpurity A)
Amoxicillin EP Impurity A(Sulbactam EP Impurity B)
Sulbactam impurity B
6-aminopenicilanic acid(6-APA)
Cloxacillin Impurity 3(Cloxacillin EP Impurity C)
Dicloxacillin Impurity 3(Dicloxacillin EP Impurity C)
Flucloxacillin Impurity 3(Flucloxacillin EP Impurity C)
Piperacillin Impurity 8(EP Impurity H)
Sulbactam Impurity 2(Sulbactam EP Impurity B)