Imipenem
- CAS No.
- 74431-23-5
- Chemical Name:
- Imipenem
- Synonyms
- Imipenem Monohydrate≥ 96% (HPLC);CS-342;MK-0787;Imipenem;lmipemide;EOS-61603;Imipenem（b）;Imipenem hydrate;Tienam monohydrate;Imipenem n-Hydrate
- CBNumber:
- CB8695769
- Molecular Formula:
- C12H19N3O5S
- Molecular Weight:
- 317.36
- MOL File:
- 74431-23-5.mol
- Modify Date:
- 2024/5/29 17:48:59
| Melting point | 193-198°C |
|---|---|
| Boiling point | 567℃ |
| RTECS | CL5446516 |
| Flash point | >110°(230°F) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: >5mg/mL |
| pka | pKa 3.2/9.9(H2O,t = 25) (Uncertain) |
| form | powder |
| color | white to beige |
| Water Solubility | Soluble in water at 5mg/ml |
| CAS DataBase Reference | 74431-23-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| WGK Germany | 3 |
| HS Code | 2941906000 |
Imipenem price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | I0160 | Imipenem monohydrate ≥98% (HPLC) | 74431-23-5 | 5MG | ₹19116.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1796 | Imipenem Pharmaceutical Secondary Standard; Certified Reference Material | 74431-23-5 | 200MG | ₹19268.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | I0160 | Imipenem monohydrate ≥98% (HPLC) | 74431-23-5 | 25MG | ₹64939.18 | 2022-06-14 | Buy |
Imipenem Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Imipenem has a broad spectrum of antimicrobial action, which includes most clinically
significant microorganisms: Gram-positive, Gram-negative, aerobic, and anaerobic. It is
resistant with respect to most beta-lactamases of Gram-positive and Gram-negative bacteria. It is used for bacterial infections of the lower respiratory tract, infections of the urinary
and sexual tracts, infections of bones, joints, skin, soft tissues, intraabdominal and gynecological infections, bacterial septicemia, and endocarditis.
Imipenem undergoes enzymatic inactivation in the kidneys. In order to avoid this problem,
it is used in a 1:1 ratio in combination with cilastatin—the sodium salt of [R-[R,S-(Z)]]-7-[(2-
amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)aminocarbonyl-2-heptenoic acid
(32.1.3.6), which inhibits metabolisms of imipenem in the kidneys. This combination of two
compounds is also used in medicine under the name primaxin.
General Description
Chemical structure: ?-lactam
Imipenem Preparation Products And Raw materials
Raw materials
Silica glass
6-Aminopenicillanic acid
INSTANT BUFFER S70, PH7.0 (ACC. TO SOERENSEN)(50PACKS)
Trimethacrylate
Benzyl ester
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Global( 264)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| UNIMARK REMEDIES LTD | +91-022-67304000 | New Delhi, India | 37 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Pharmaffiliates Analytics & Synthetics (P) Ltd. | 91-172-5066494 | Haryana, India | 631 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 6011 | 58 | Inquiry |
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- What is Imipenem?
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74431-23-5(Imipenem)Related Search:
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Imipenem hydrate
Imipenem Monohydrate (100 mg)
Crude Grade of Imipenem
(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate, Primaxin monohydrate, Tienam monohydrate
(6 R,7 R)-7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID Monohydrate
(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate
Primaxin monohydrate
Tienam monohydrate
Imipenem monohydrate, >=98%
Imipenem Monohydrate, Antibiotic for Culture Media Use Only
(6 R,7 R)-7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID, 7-AMINO-8-OXO-3-(1-PROPENYL)-, (6R,7R)-
(6 R ,7 R ) - 7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-AZABICYLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
(5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl) amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate
Imipenem
lmipemide
MK-0787
(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.]hept-2-ene-2-carboxylic acid hydrate
[5R-[5α，6α(R^<*>^)]]-6-(1-hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate
Imipenem n-Hydrate
CS-342
EOS-61603
IMIPEMIDE MONOHYDRATE
N-Formimidoyl thienamycin monohydrate
Imipenem USP/EP/BP
Imipenem monohydrate (High purity)
Imipenem 1-hydrate
?mipenem monohydrate Crude
(6R,7R)-7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-azabicyclo[4.2...
Imipenem MonohydrateQ: What is
Imipenem Monohydrate Q: What is the CAS Number of
Imipenem Monohydrate Q: What is the storage condition of
Imipenem Monohydrate
Imipenem crude(monohydrate non sterile)
Imipenem crude(monohydrate non sterile)
Imipenem Monohydrate (1337809)
Imipenem Monohydrate≥ 96% (HPLC)
bacteria,Inhibitor,N-Formimidoyl thienamycin,P. aeruginosa,ntibiotic,MK0787,Imipenem monohydrate,MK 0787,MK-0787,infection,inhibit,Bacterial,Antibiotic,thienamycin
Imipenem（b）
74431-23-5
C12H17N3O4SH2O
ROXIT
Intermediates & Fine Chemicals
Pharmaceuticals