4-Nitrobenzyl hydrogen malonate
![4-Nitrobenzyl hydrogen malonate Structure](CAS/GIF/77359-11-6.gif)
- CAS No.
- 77359-11-6
- Chemical Name:
- 4-Nitrobenzyl hydrogen malonate
- Synonyms
- 4-NITROBENZYLMALONATE;P-NITROBENZYLMALONATE;Mononitrobenzyl malonate;2-(4-Nitrobenzyl)malonate;MONO-4-NITROBENZYL MALONATE;MONO P-NITRO BENZYL MALONATE;4-Nitrobenzyl hydrogen malote;Mono-4-nitrobenzylMalonate>Mono-4-nitrobenzylmalonicacides;4-nitrobenzyl hydrogen malonate
- CBNumber:
- CB1714632
- Molecular Formula:
- C10H9NO6
- Molecular Weight:
- 239.18
- MOL File:
- 77359-11-6.mol
- Modify Date:
- 2024/8/24 19:19:26
Melting point | 109 °C |
---|---|
Boiling point | 455.8±30.0 °C(Predicted) |
Density | 1.447±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | soluble in Methanol |
form | powder to crystal |
pka | 2.49±0.32(Predicted) |
color | White to Almost white |
InChIKey | RIGFMUNSTCPGNP-UHFFFAOYSA-N |
CAS DataBase Reference | 77359-11-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H341 |
Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
HS Code | 2917399590 |
4-Nitrobenzyl hydrogen malonate price More Price(2)
4-Nitrobenzyl hydrogen malonate Chemical Properties,Uses,Production
Uses
4-Nitrobenzyl hydrogen malonate is a reagent used in the synthesis of (±)-thienamycin, a β-Lactam antibiotics. Also, it is useful for chiral key intermediate of carbapenem syntheses.
Preparation
Preparation of mono-4-nitrobenzyl malonate:
In a flame-dried 150 mL pressure tube under argon, add 5.00 g (34.7 mmol) of Meldrum's acid and 40 mL of anhydrous MeCN.
Add 5.58 g (36.4 mmol) of p-nitrobenzyl alcohol to the resulting solution.
Cap the tube tightly and reflux the reaction overnight.
Concentrate the reaction mixture under reduced pressure.
Purify the residue using column chromatography with a 55/45 hexane/EtOAc mixture.
The resulting product is mono-4-nitrobenzyl malonate with a yield of 87%.
4-Nitrobenzyl hydrogen malonate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 293)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Ralington Pharma | 91-79-48911722 | Gujarat, India | 312 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
SAURAV CHEMICALS LIMITED | (+91) 01762522312 | New Delhi, India | 7 | 58 | Inquiry |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |
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Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
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