4-Nitrobenzyl chloride
- CAS No.
- 100-14-1
- Chemical Name:
- 4-Nitrobenzyl chloride
- Synonyms
- 1-(Chloromethyl)-4-nitrobenzene;P-NITROBENZYL CHLORIDE;p-nitrochloride;AKOS BBS-00003951;Nitrochlorobenzyl;Nitrobenzylchloride;Nitrobenzyl chlorid;4-NITROBENZYL CHLORIDE;à-chloro-4-nitrotoluene;α-Chloro-4-nitrotoluene
- CBNumber:
- CB9852554
- Molecular Formula:
- C7H6ClNO2
- Molecular Weight:
- 171.58
- MOL File:
- 100-14-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
| Melting point | 71 °C |
|---|---|
| Boiling point | 112 °C (0.6 mmHg) |
| Density | 1.3246 (rough estimate) |
| refractive index | 1.5647 (estimate) |
| solubility | chloroform: soluble50mg/mL, clear to very slightly hazy, faintly yellow |
| form | Crystalline Needles or Powder |
| color | Light yellow |
| BRN | 387187 |
| Stability | Stable. Incompatible with strong oxidizing agents, bases, amines, moisture, alcohols. Corrodes steel. Reacts slowly with water. Combustible. |
| CAS DataBase Reference | 100-14-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Nitrobenzyl chloride(100-14-1) |
| EPA Substance Registry System | 1-(Chloromethyl)-4-nitrobenzene (100-14-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314 | |||||||||
| Precautionary statements | P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 22-34-36 | |||||||||
| Safety Statements | 26-36/37/39-45-27 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XS9093000 | |||||||||
| F | 4.8-19-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29049090 | |||||||||
| Hazardous Substances Data | 100-14-1(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
4-Nitrobenzyl chloride price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 140112 | 4-Nitrobenzyl chloride 99% | 100-14-1 | 25G | ₹2321 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 140112 | 4-Nitrobenzyl chloride 99% | 100-14-1 | 25G | ₹2321 | 2022-06-14 | Buy |
| Sigma-Aldrich | 140112 | 4-Nitrobenzyl chloride 99% | 100-14-1 | 100G | ₹15772.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 140112 | 4-Nitrobenzyl chloride 99% | 100-14-1 | 100G | ₹15772.25 | 2022-06-14 | Buy |
| ALFA India | ALF-A15749-30 | 4-Nitrobenzyl chloride, 99% | 100-14-1 | 250g | ₹25220 | 2022-05-26 | Buy |
4-Nitrobenzyl chloride Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
4-Nitrobenzyl chloride was used to prepare unsymmetrically N,N′-bis(substituted) 4,13-diaza-18-crown-6-ether derivatives.
Definition
ChEBI: A C-nitro compound that is nitrobenzene in which the hydrogen at position 4 is replaced by a chloromethyl group.
Production Methods
Chlorination of 4-nitrotoluene at 190 ℃ without catalyst gives 4-Nitrobenzyl chloride. The alternative process of nitration of benzylchloride coproduces 2-nitrobenzyl chloride and requires a difficult separation stage.
General Description
Solid.
Air & Water Reactions
May react slowly with water.
Reactivity Profile
Incompatible with sodium hydroxide. [EPA, 1998]. A halogenated aromatic nitro compound. Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups.
Health Hazard
Poisonous if swallowed or dust is inhaled.
Fire Hazard
Incompatible with sodium hydroxide.
Potential Exposure
A chloronitrobenzene compound, used in organic synthesis.
Shipping
UN3261 Corrosive solid, acidic, organic, n.o.s., Hazard class: 8; Labels: 8—Corrosive material, Technical Name Required. UN1578 Chloronitrobenzenes, solid or liquid, Hazard Class: 6.1; Labels: 6.1—Poisonous materials.
Purification Methods
Crystallise the chloride from CCl4, dry diethyl ether, or n-heptane, and dry it under vacuum. IRRITANT.[Beilstein 5 IV 856.]
Incompatibilities
Can react with sulfuric acid. Keep away from oxidizers, amines, bases: sodium hydroxide, and potassium hydroxide; may cause fire and explosions. Incompatible with strong oxidizing and reducing agents such as hydrides, certain amines, nitrides, azo/diazo compounds, alkali metals (potassium), and epoxides. Corrodes steel, some plastics and human tissue.
4-Nitrobenzyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
chevron_right