(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Structure
CAS No.
86286-50-2
Chemical Name:
(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE
Synonyms
4,5-diphenyl-2-oxazolidinone;(4R,5S)-4,5-DIPHENYLOXAZOLIDIN-2-ONE;(4R,5S)-4,5-Diphenyl-2-oxazolidinone;2-Oxazolidinone, 4,5-diphenyl-, (4R,5S)-;(4R,5S)-cis-4,5-Diphenyloxazolidin-2-one;(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE;(4R,5S)-4,5-Diphenyl-2-oxazolidinone,99%e.e.;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, ee: 98%;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, 98%, ee: 98%
CBNumber:
CB1717996
Molecular Formula:
C15H13NO2
Molecular Weight:
239.27
MOL File:
86286-50-2.mol
Modify Date:
2022/8/15 17:37:21

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Properties

Melting point 227-230 °C (lit.)
Boiling point 466.6±45.0 °C(Predicted)
Density 1.192±0.06 g/cm3(Predicted)
pka 11.56±0.60(Predicted)
optical activity [α]20/D 57±4°, c = 2 in methanol

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29029090

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 454540 (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone 98% 86286-50-2 1G ₹10175.5 2022-06-14 Buy
Product number Packaging Price Buy
454540 1G ₹10175.5 Buy

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Chemical Properties,Uses,Production

Chemical Properties

White powder or crystal

Uses

Versatile chiral auxiliary for asymmetric synthesis. For a recent review, see Aldrichimica Acta .

Preparation

To a stirred suspension of commercially available (10.0 g, 47 mmol) and triethylamine (14.4 mL, 0.10 mol) in dichloromethane (100 mL), diphosgene (3.0 mL, 25 mmol) was added dropwise at 0 °C and the mixture was stirred for 1 h at the same temperature. After concentration in vacuo, the residue was poured into water to precipitate crystals. The crystals were collected by filtration, successively washed with 10% HCl and H2O, and dried in vacuo at 50–60 °C for 3 h to afford 593a as colorless crystals (10.9 g, 97%).

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Suppliers

Global( 35)Suppliers
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A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 13675144456 China 11442 58 Inquiry
Combi-Blocks Inc. 858 635 8950 United States 6632 69 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 China 29778 58 Inquiry
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 18112977050 China 16687 50 Inquiry
Bide Pharmatech Ltd. 400-1647117 15221909166 China 63720 58 Inquiry
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 China 18488 58 Inquiry
Bide Pharmatech Ltd. 400-6005915 China 39661 58 Inquiry
(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE (4R,5S)-4,5-Diphenyl-2-oxazolidinone (4R,5S)-cis-4,5-Diphenyloxazolidin-2-one (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, ee: 98% (4R,5S)-4,5-Diphenyl-2-oxazolidinone,99%e.e. (4R,5S)-4,5-DIPHENYLOXAZOLIDIN-2-ONE (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, 98%, ee: 98% 4,5-diphenyl-2-oxazolidinone 2-Oxazolidinone, 4,5-diphenyl-, (4R,5S)- 86286-50-2 Oxazolidinone Derivatives Asymmetric Synthesis Chiral Auxiliaries Benzene derivatives Asymmetric Synthesis Chiral Auxiliaries Oxazolidinone Derivatives