Phenelzine Sulfate
- CAS No.
- 156-51-4
- Chemical Name:
- Phenelzine Sulfate
- Synonyms
- wl7;p1531;S-1544;ep-411;kalgan;alazin;N-1544A;mao-rem;alacine;alazine
- CBNumber:
- CB1719066
- Molecular Formula:
- C8H14N2O4S
- Molecular Weight:
- 234.27
- MOL File:
- 156-51-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:01
| Melting point | 166.5-167.5 °C |
|---|---|
| storage temp. | 2-8°C |
| solubility | Freely soluble in water; practically insoluble in ethanol (96%) and in ether . |
| form | A solid |
| color | White to off-white |
| Merck | 13,7300 |
| CAS DataBase Reference | 156-51-4 |
| IARC | 3 (Vol. 24, Sup 7) 1987 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MV8750000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2928002500 | |||||||||
| Toxicity | LD50 orally in mice: 156 mg/kg (Gylys) | |||||||||
| NFPA 704 |
|
Phenelzine Sulfate price More Price(2)
Phenelzine Sulfate Chemical Properties,Uses,Production
Chemical Properties
A white powder or pearly platelets.
Uses
Phenelzine Sulfate is a hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidep ressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders.
General Description
Phenelzine sulfate, 2-(phenylethyl)hydrazine sulfate(Nardil), is an effective antidepressant agent. A mechanismbasedinactivator, it irreversibly inactivates the enzyme orits cofactor, presumably after oxidation to the diazine,which can then break up into molecular nitrogen, a hydrogen atom, and a phenethyl free radical. The latter would bethe active species in irreversible inhibition.
Safety Profile
Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: wakefulness, blood pressure lowering, constipation, hepatitis, fibrous hepatitis. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. Used as a drug for the treatment of depression. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Phenelzine Sulfate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TYCHE INDUSTRIES LTD | +91 40 2354 1688 | New Delhi, India | 2 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29900 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | China | 3148 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26165 | 58 | Inquiry |