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1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE
- CAS No.
- 73465-43-7
- Chemical Name:
- 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE
- Synonyms
- DMM;DMJ;DMJ, HYDROCHLORIDE;DEOXYMANNOJIRIMYCIN HCL;1-DeoxymannojirimycineHCl;1-DEOXYMANNOJIRIMYCIN HCL;DEOXYMANNONOJIRIMYCIN HCL;DEOXYMANNOJIRIMYCIN, HYDROCHLORIDE;1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE;1-Deoxymannojirimycinehydrochloride
- CBNumber:
- CB1768822
- Molecular Formula:
- C6H14ClNO4
- Molecular Weight:
- 199.63
- MOL File:
- 73465-43-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 183-185°C |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: soluble10mg/mL |
| form | Powder |
| color | white to off-white |
| Water Solubility | Soluble in water (50 mM) |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months. |
| CAS DataBase Reference | 73465-43-7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2941900000 | |||||||||
| NFPA 704 |
|
1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D9160 | 1-Deoxymannojirimycin hydrochloride | 73465-43-7 | 1MG | ₹10565.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D9160 | 1-Deoxymannojirimycin hydrochloride | 73465-43-7 | 5MG | ₹23576.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D9160 | 1-Deoxymannojirimycin hydrochloride | 73465-43-7 | 10MG | ₹40366.43 | 2022-06-14 | Buy |
1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Chemical Properties,Uses,Production
Description
1-Deoxymannojirimycin is a specific inhibitor of class I α-1,2-mannosidase (IC50 = 0.02 μM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome. By inhibiting α-1,2-mannosidase activity, this compound generates N-linked oligosaccharides with high mannose content, preventing misfolded protein degradation. This compound has been used for studies on glycoprotein processing and as a model for the development of anticancer and antiviral therapies.
Chemical Properties
White Crystalline Solid
Uses
Deoxymannojirimycin has been shown to be a potent inhibitor of the mammalian Golgi alpha- mannosidase 1 activity, blocking the conversion of high-mannose oligosaccharides to complex-type oligosaccharides. However, it does not inhibit the biosynthesis of lipid- linked oligosaccharides.
1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Suppliers
Global( 108)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25196 | 58 | Inquiry |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | China | 5990 | 58 | Inquiry |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Wuhan Fortuna Chemical Co.,Ltd | +8618007136271 | China | 5639 | 58 | Inquiry |
| Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 | China | 5821 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
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