ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Deoxynucleotides and their analogs >2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate

2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate

2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate Structure
CAS No.
134790-39-9
Chemical Name:
2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate
Synonyms
Gemcitabine alpha-Anomer;2,2-DIFLOURO-2-DEOXYCYTIDINE-3,5-DIBENZOATE;2’,2’-Difluoro-2’-deoxycyodine-3’,5’-dibenzoate;(2R,3R,5R)-5-(4-aMino-2-oxopyriMidin-1(2H)-yl)-2-(benzoyloxyMethyl)-4,4-difluorotetrahydrofuran-3-yl benzoate;GCTB-T9;T9 of Gemcitabine;Chloropurine riboside;GeMcitabine InterMediate 9;Gemcitabine T9 Intermediate;(2R,3R,5R)-5-(4-amino-2-oxopyrimidin
CBNumber:
CB1855625
Molecular Formula:
C23H19F2N3O6
Molecular Weight:
471.41
MOL File:
134790-39-9.mol
MSDS File:
SDS
Modify Date:
2024/3/28 13:39:29

2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate Properties

Melting point 229-232°C
Boiling point 608.4±65.0 °C(Predicted)
Density 1.45±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO
form Solid
pka 4.26±0.10(Predicted)
color Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280
HS Code  2934999090

2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate Chemical Properties,Uses,Production

Chemical Properties

Tan Solid

Uses

A (-anomer) intermediate of Gemcitabine; antitumor compound

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2',2'-difluoro-2'-deoxycytidine-3',5'-dibenzoate Cytidine, 2'-deoxy-2',2'-difluoro-, 3',5'-dibenzoate 2'-Deoxy-3',5'-di-O-benzoyl-2',2'-difluorocytidine, >=97% 2-DEOXY-2,2-DIFLUORO-35-BIS-O-BENZOYLEYTIDINE MONOHYDROCHLORIDE T9 of Gemcitabine 2'-deoxy-2,2'-difluoro-3,5-dibenzyl-cytidine 2',2'-Difluoro-2'-deoxycyodine-3',5'–dibenzoate ( or its salt) 2'-deoxy-2',2'-difluoro-3',5'-di-O-benzoates-cytidine (or its salt) Cytidine, 2'-deoxy-2',2'-difluoro-, 3',5'-dibenzoate (9CI) 2’-Deoxy-2’,2’-difluoro-3’,5’-bis-O-benzoylcytidine 2’-Deoxy-3’,5’-di-O-benzoyl-2’,2’-difluorocytidine Chloropurine riboside 3',5'-Di-O-benzoyl-2'-deoxy-2',2'-difluorocytidine GeMcitabine InterMediate 9 T9, 2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate 2'-Deoxy-2',2'-difluro-3'5'-bis-O-benzoylcytidine 2'-Deoxy-2',2'-difluorocytidine-3',5'-dibenzoate, 1-(3,5-Bis-O-benzoyl-2-deoxy-2,2-difluoro-beta-D-ribofuranosyl)cytosine 3',5'-Bis-O-benzoyl-2'-deoxy-2',2'-difluorocytidine [(2R,3S,5R)-5-(4-aMino-2-oxo-1,2-dihydropyriMidin-1-yl)-3-(benzoyloxy)-4,4-difluorooxolan-2-yl]Methyl benzoate 2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate (Gemcitabine impurity) 3',5'-Di-O-benzoyl-2',2'-difluoro-2'-deoxy cytidine (2R,3R,5R)-5-(4-amino-2-oxopyrimidin Gemcitabine impurity 4/2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate 2-[[5-(4-amino-2-oxo-1-pyrimidinyl)-3-(2-carboxylatophenyl)-4,4-difluoro-3-hydroxy-2-oxolanyl]-hydroxymethyl]benzoate 2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate USP/EP/BP (2R,3R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4,4-difluorotetrahydrofuran-3-yl benzoate Gemcitabine T9 Intermediate (2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-(benzoyloxy)-4,4-difluorooxolan-2-yl]methyl benzoate 2’,2’-Difluoro-2’-deoxycyodine-3’,5’-dibenzoate (2R,3R,5R)-5-(4-aMino-2-oxopyriMidin-1(2H)-yl)-2-(benzoyloxyMethyl)-4,4-difluorotetrahydrofuran-3-yl benzoate Gemcitabine alpha-Anomer 2,2-DIFLOURO-2-DEOXYCYTIDINE-3,5-DIBENZOATE 2',2'- difluoro -2'- deoxycytosine nucleoside -3',5'- dibenzoate GCTB-T9 2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate 2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate (T9) 2',2'- difluoro -2'- deoxycytosine nucleoside -3',5'- dibenzoate 3',5'-Di-O-benzoyl-2',2'-difluoro-2'-deoxy cytidine 134790-39-9 C23H19F2N3O6 Amines Bases & Related Reagents Heterocycles Nucleotides API intermediates