D-fructose 6-(dihydrogen phosphate)

D-fructose 6-(dihydrogen phosphate) Structure
CAS No.
643-13-0
Chemical Name:
D-fructose 6-(dihydrogen phosphate)
Synonyms
Fructose 6-phosphate;F6P;fruc6p;Fru6-P;FRUCTOSE-6P;lactacidogen;fructose-6-P;D-fructose-6-P;A-D-fructose-6-P;Methotrexate Impurity 23
CBNumber:
CB1917691
Molecular Formula:
C6H13O9P
Molecular Weight:
260.14
MOL File:
643-13-0.mol
Modify Date:
2025/4/30 17:58:12

D-fructose 6-(dihydrogen phosphate) Properties

alpha D21 +2.5° (c = 3), Meyerhof, Lohmann, Biochem. Z. 185, 117 (1927); D +1.2° (c = 0.9), Lohmann, ibid. 262, 145 (1933)
Boiling point 697.7±65.0 °C(Predicted)
Density 1.840±0.06 g/cm3(Predicted)
pka 1.83±0.10(Predicted)
form Solid
color White to off-white
EPA Substance Registry System D-Fructose, 6-(dihydrogen phosphate) (643-13-0)

SAFETY

Risk and Safety Statements

RIDADR  1759
HazardClass  8
PackingGroup  III

D-fructose 6-(dihydrogen phosphate) Chemical Properties,Uses,Production

Purification Methods

Crystallise fructose-6-phosphate as the barium salt from water by adding 4-volumes of EtOH. The barium can be removed by passage through the H+ form of a cation exchange resin, and the free acid is collected by freeze-drying. Alternatively the Ba salt is dissolved in H2O, and one equivalent of Na2SO4 is added in small portions with stirring, filter off BaSO4 and freeze dry to give the Na salt. The 6-phosphate hydrolyses more slowly than the 1-phosphate and considerably slower than pyrophosphoric acid (102 times) and triphosphoric acid (103 times). [Neuberg Biochem Zeitschrift 88 432 1918, pKa: Meyerhof & Lohmann Biochem Zeitschrift 185 113, 131 1927, Neuberg et al. Arch Biochem 3 33, 40 1944, Hydrolysis: Friess J Am Chem Soc 74 5521 1954, Beilstein 1 I 464, 1 IV 4423, H 31 537.]

D-fructose 6-(dihydrogen phosphate) Preparation Products And Raw materials

Raw materials

Preparation Products

D-fructose 6-(dihydrogen phosphate) Suppliers

Global( 27)Suppliers
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TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32248 58 Inquiry
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Finetech Industry Limited 027-87465837 19945049750 China 9650 58 Inquiry
Cato Research Chemicals Inc. 18933936954 China 17709 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24753 58 Inquiry
lactacidogen D-fructose 6-(dihydrogen phosphate) [(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxo-hexoxy]phosphonic acid D-Fructose 6-phosphoric acid Fru6-P Fructose 6-phosphoric acid Fructose-6-phosphoric acid A-D-fructose-6-P D-fructose-6-P fruc6p FRUCTOSE-6P fructose-6-P keto-D-fructose 6-phosphate Beta-D-Fructose 6 phosphate (β-D-F6P) Fructose 6-phosphate F6P Methotrexate Impurity 23 643-13-0 C6H11O6PO3H2