Dexamethasone Impurity I

Dexamethasone Impurity I Structure
CAS No.
14622-47-0
Chemical Name:
Dexamethasone Impurity I
Synonyms
DB11(16β-Methyl Epoxide);Carbamazepine Impurity 23;Dexamethasone-9(11)-alpha-Epoxide;Dexamethasone impurity 3/Dexamethasone EP Impurity I;Dexamethasone Impurity 9(Dexamethasone EP Impurity I);Dexamethasone EP Impurity I / Dexamethasone-9(11)-αEpoxide;17α,21-Dihydroxy-9β,11β-epoxy-16β-methyl-pregnadien-(1.4)-dion-(3.20);(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-Methylpregna-1,4-diene-3,20-dione;(11a,16a)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione;(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
CBNumber:
CB21009572
Molecular Formula:
C22H28O5
Molecular Weight:
372.45
MOL File:
14622-47-0.mol
MSDS File:
SDS
Modify Date:
2024/5/15 13:17:26

Dexamethasone Impurity I Properties

Melting point >211°C
Boiling point 564.9±50.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka 12.56±0.70(Predicted)
color White to Pale Red

Dexamethasone Impurity I Chemical Properties,Uses,Production

Uses

(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, can be used for the synthesis of Calicoferol E, a vitamin D3 analogues.

Dexamethasone Impurity I Preparation Products And Raw materials

Raw materials

Preparation Products

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Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 China 9911 50 Inquiry
16β-METHYL EPOXIDE(DB-11), 17α,21-DIHYDROXY-9β,11β,EPOXY-16β-METHYLPREGN-1,4-DIENE-3,20-DIONE 16BETA-METHYL EPOXIDE(DB-11): 17ALPHA,21-DIHYDROXY-9BETA,11BETA,EPOXY-16BETA-METHYLPREGN-1,4-DIENE-3,20-DIONE DB11(16β-Methyl Epoxide) (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-Methylpregna-1,4-diene-3,20-dione Dexamethasone-9(11)-alpha-Epoxide (4aS,4bR,5aR,6aS,7R,8R,9aS,9bS)-7-hydroxy-7-(2-hydroxyacetyl)-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one Dexamethasone Impurity 9(Dexamethasone EP Impurity I) Dexamethasone impurity 3/Dexamethasone EP Impurity I 17α,21-Dihydroxy-9β,11β-epoxy-16β-methyl-pregnadien-(1.4)-dion-(3.20) Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-16-methyl-, (11α,16α)- (11a,16a)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione Dexamethasone EP Impurity I / Dexamethasone-9(11)-αEpoxide (4aS,4bR,5aR,6aS,7R,8R,9aS,9bS)-7-hydroxy-7-(2-hydroxyacetyl)-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one? (Dexamethasone Impurity) (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregnα-1,4-diene-3,20-dione (11Alpha,16Alpha)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione Carbamazepine Impurity 23 14622-47-0 Pharmaceuticals, Intermediates & Fine Chemicals, Steroids