ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Chloropyrimidine >4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine

4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine

CAS No.: 42754-96-1

Chemical Name:: 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine

Synonyms: 4,6-dichloro-2H-pyrazolo[3,4-d]pyrimidine;SKL327;6-Dichloro-1H-pyrazolo[3;4,6-dichloropyrrolo[2,3-d]pyrimidine;4,6-Dichloropyrazolo[3,4-d]pyriMidine;4,6-dichloro-1H-pyrazolo[3,4-d]pP03119ine;4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE;4,6-Dichloro-1H-pyrazole[3,4-D]pyriMidine;1H-Pyrazolo[3,4-d]pyrimidine,4,6-dichloro-;4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE(RS20012005)

CBNumber:: CB21215944

Molecular Formula:: C5H2Cl2N4

Molecular Weight:: 189

MOL File:: 42754-96-1.mol

MSDS File:: SDS

Modify Date:: 2024/9/13 14:33:30

Request For Quotation

4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Properties

Melting point	145 °C (decomp)
Boiling point	251.9±50.0 °C(Predicted)
Density	2.02±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	solid
pka	7.90±0.20(Predicted)
color	Off-white to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	T
Risk Statements	25
Safety Statements	45-24/25
RIDADR	UN2811
HazardClass	IRRITANT
HS Code	29335990

4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Chemical Properties,Uses,Production

Chemical Properties

Yellow solid

Synthesis

To a solution of 2,4,6-trichloropyrimidine-5-carbaldehyde (19.0 g, 990 mmol) in methanol (300 mL) was added drop-wise a solution of hydrazine monohydrate (4.8 mL) in methanol (80 mL) at 0 °C followed by drop-wise addition of triethylamine (13 mL) in methanol (80 mL) at 0 °C. The mixture was stirred at the same temperature for 30 mm. The solvent was removed, and the residue was purified by flash chromatography to afford 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine (10.3 g, 62 % yield) as a yellow solid. ‘H NMR (CDC13, 400IVIHz): 11.56 (br, 1H), 8.43 (s, 1H). MS m/z 190.68 [M+1].

4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Preparation Products And Raw materials

Raw materials

UREA-13C Phosphorus oxychloride Urea 3-Amino-4-pyrazolecarbonitrile Acetic acid

Sodium hydroxide N,N-Diethylaniline Sulfuric acid

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Preparation Products

4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Suppliers

Global( 230)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED	+919966658228	Hyderabad, India	486	58	Inquiry
MANVI BIOPHARMA PVT LTD,	+91-9951015911 +91-9951015911	Hyderabad, India	86	58	Inquiry
REAX CHEMICALS	+91-9347443900 +91-9347443900	Hyderabad, India	169	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32835	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29899	58	Inquiry
Accela ChemBio Inc.	+1-858-6993322	United States	19751	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49403	58	Inquiry

Supplier	Advantage
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED	58
MANVI BIOPHARMA PVT LTD,	58
REAX CHEMICALS	58
A.J Chemicals	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Spectrum

4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE(42754-96-1)¹HNMR

42754-96-1(4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine)Related Search:

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4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE 1H-Pyrazolo[3,4-d]pyrimidine,4,6-dichloro- 4,6-dichloropyrrolo[2,3-d]pyrimidine 4,6-Dichloro-1H-pyrazole[3,4-D]pyriMidine 4,6-Dichloropyrazolo[3,4-d]pyriMidine 6-Dichloro-1H-pyrazolo[3 4,6-dichloro-1H-pyrazolo[3,4-d]pP03119ine 4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE(RS20012005) SKL327 4,6-dichloro-2H-pyrazolo[3,4-d]pyrimidine 42754-96-1 C5H2N4Cl2 Aromatics Heterocycles Building Blocks Pyrazolo[x,x-y]pyridine Heterocycle-Pyrimidine series CHIRAL CHEMICALS