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Methylophiopogonanone A

Methylophiopogonanone A Structure
CAS No.
74805-92-8
Chemical Name:
Methylophiopogonanone A
Synonyms
Methylophiopogonanone A;R-Methylophiopogonanone A;8-Methylophiopogonanone A;Methylophiopogonanone A (MO-A);Methylophiopogonanone A(R-Methylophiopogonanone A);3-(benzo[d][1,3]dioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethylchroman-4-one;(3R)-3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydrochromen-4-one;(3R)-3-(1,3-Benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 3-(1,3-benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl-, (3R)-
CBNumber:
CB21267822
Molecular Formula:
C19H18O6
Molecular Weight:
342.34
MOL File:
74805-92-8.mol
MSDS File:
SDS
Modify Date:
2023/9/1 17:37:15

Methylophiopogonanone A Properties

Boiling point 580.1±50.0 °C(Predicted)
Density 1.410
solubility Soluble in chloroform and methanol;
form powder
pka 8.24±0.40(Predicted)
color Light yellow
Water Solubility insoluble in water

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Methylophiopogonanone A Chemical Properties,Uses,Production

Description

Methylophiopogonanone A is a homoisoflavonoid that has been found in O. japonicus roots and has diverse biological activities. It increases the uptake of rosuvastatin (Item Nos. 12029 | 18813) and atorvastatin in HEK293T cells expressing human organic anion transporting polypeptide 1B1 (OATP1B1; EC50s = 11.33 and 6 μM, respectively). Methylophiopogonanone A scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS radicals in cell-free assays. In vivo, methylophiopogonanone A (10 mg/kg) decreases body weight gain and reduces serum and hepatic lipid levels in a rat model of high-fat diet-induced hyperlipidemia. It also reduces infarct size and myocardial apoptosis in mouse model of ischemia-reperfusion injury induced by transient occlusion of the left anterior descending coronary artery.

Methylophiopogonanone A Preparation Products And Raw materials

Raw materials

Preparation Products

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Methylophiopogonanone A Methylophiopogonanone A(R-Methylophiopogonanone A) 8-Methylophiopogonanone A (3R)-3-(1,3-Benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl-4H-1-benzopyran-4-one R-Methylophiopogonanone A Methylophiopogonanone A (MO-A) (3R)-3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydrochromen-4-one 4H-1-Benzopyran-4-one, 3-(1,3-benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl-, (3R)- 3-(benzo[d][1,3]dioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethylchroman-4-one 74805-92-8 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract