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N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE)

CAS No.: 1477-57-2

Chemical Name:: N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE)

Synonyms: SKL878;r-010-tk;win18441;win18446;win18,446;NSC 59354;bisdiamine;FERTILYSIN;bis-diamine;Fertilysine

CBNumber:: CB2146249

Molecular Formula:: C12H20Cl4N2O2

Molecular Weight:: 366.11

MOL File:: 1477-57-2.mol

MSDS File:: SDS

Modify Date:: 2024/7/26 17:49:17

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N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) Properties

Melting point	118-120 °C
Boiling point	530℃
Density	0.726
refractive index	1.6200 (estimate)
Flash point	275℃
storage temp.	Inert atmosphere,2-8°C
solubility	Acetone (Very Slightly), DMSO (Slightly), Methanol (Sparingly, Heated, Sonicated
pka	12.28±0.46(Predicted)
form	Solid
color	White to Off-White
CAS DataBase Reference	1477-57-2

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Warning

Hazard statements

H312+H332-H351

Precautionary statements

P202-P261-P280-P302+P352+P312-P304+P340+P312-P308+P313

Hazard Codes

Risk Statements

20/21/22-40

Safety Statements

24/25-45-36

Toxicity

LD50 orally in mice: >16000 mg/kg (Coulston)

NFPA 704

	1
2		0

N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SML3187	WIN 18446 ≥98% (HPLC)	1477-57-2	50MG	₹11528.63	2022-06-14	Buy

Product number	Packaging	Price	Buy
SML3187	50MG	₹11528.63	Buy

N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

Win 18446 was shown to inhibit the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis and in the embryonic murine gonad.

Definition

ChEBI: A carboxamide that is 1,8-diaminooctane in which a hydrogen attached to each of the amino groups has been replaced by a dichloroacetyl group. Inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2). Inhibits the biosynthesis of retinoic acid from retinol in neon tal and adult murine testis. It down-regulates sex related genes in zebrafish.

Safety Profile

Poison by intraperitoneal route.Human systemic effects by ingestion: nausea andvomiting. Human reproductive effects by ingestion:changes in spermatogenesis. An experimental teratogen.Other experimental reproductive effects. Human mutationdata reporte

N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) Preparation Products And Raw materials

Raw materials

Preparation Products

N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) Suppliers

Global( 96)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-15536356810	China	2063	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Finetech Industry Limited	+86-27-87465837 +8618971612321	China	9624	58	Inquiry
CD Chemical Group Limited	+8615986615575	China	20356	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	+8618235132063	China	3725	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry

Supplier	Advantage
CHEMSWORTH	30
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Finetech Industry Limited	58
CD Chemical Group Limited	58
LEAP CHEM CO., LTD.	58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd	58
Amadis Chemical Company Limited	58

N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) Spectrum

N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE)(1477-57-2)¹HNMR N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE)(1477-57-2)IR1 N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE)(1477-57-2)IR2

1477-57-2(N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE))Related Search:

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N,N'-DIMETHYL-1,8-OCTANEDIAMINE 2-Chloro-N-methylacetamide N-Methylacetamide N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) N-METHYLHEXYLAMINE

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FERTILYSIN N,N'-BIS(DICHLOROACETYL)-1,8-OCTAMETHYLENEDIAMINE N,N'-OCTA-METHYLENE-BIS[2,2-DICHLOROACETAMIDE] N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) bisdiamine bis-diamine n,n’,1,8-octanediylbis(2,2-dichloro-acetamid n,n’-bis(dichloroacetyl)-1,8-diaminooctane n,n’-bis(dichloroacetyl)-1,8-octanediamine n,n’-octamethylenebis(2,2-dichloro-acetamid n,n’-octamethylenebis(2,2-dichloroactamide) n,n-bis(dichloroacetyl)-1,8-octanediamine r-010-tk win18,446 win18441 win18446 NSC 59354 N,N''-OCTMETHYLENEBIS (DICHLOROACETAMIDE) N,N'-(1,8-Octanediyl)bis(2,2-dichloroacetamide) N,N'-Octamethylenebis(dichloroacetamide),97% N,N'-(Octane-1,8-diyl)bis(2,2-dichloroacetaMide) AcetaMide,N,N'-1,8-octanediylbis[2,2-dichloro- Fertilysine SKL878 WIN 18446,Stra8,testis,spermatogenesis,inhibit,Win18446,Aldehyde Dehydrogenase (ALDH),Testes,Win-18446,Inhibitor 2,2-dichloro-N-[8-[(2,2-dichloroacetyl)amino]octyl]acetamide N,N'-(Octane-1,8-diyl)bis(2,2-dichloroacetamide) N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) ACETAMIDE,N,N'-1,8-OCTANEDIYLBIS[2,2-DICHLORO- 1477-57-2 C12H20Cl4N2O2