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CALPAIN INHIBITOR XII

CALPAIN INHIBITOR XII Structure
CAS No.
181769-57-3
Chemical Name:
CALPAIN INHIBITOR XII
Synonyms
CALPAIN INHIBITOR XII;Z-L-NVA-CONH-CH2-2-PY;PLVWMBFPIAQRHK-UHFFFAOYSA-N;(Rac)-Calpain Inhibitor XII;benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate;Carbamic acid, [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-, phenylmethyl ester (9CI)
CBNumber:
CB2243292
Molecular Formula:
C26H34N4O5
Molecular Weight:
482.57
MOL File:
Mol file
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:03
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CALPAIN INHIBITOR XII Properties

Density 1.167±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≤16mg/ml in ethanol;16mg/ml in DMSO;20mg/ml in dimethyl formamide
form crystalline solid
pka 10.58±0.46(Predicted)
color White to yellow

CALPAIN INHIBITOR XII Chemical Properties,Uses,Production

Description

Calpain inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki = 19 nM), with lower affinities for calpain II (m-calpain, Ki = 120 nM) and cathepsin B (Ki = 750 nM). Calpain inhibitors, including this compound, have been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.

Uses

A cell-permeable dipeptidyl -ketoamide compound that acts as a potent, selective, reversible, and active site inhibitor of calpain-1

CALPAIN INHIBITOR XII Preparation Products And Raw materials

Raw materials

Preparation Products

CALPAIN INHIBITOR XII Suppliers

Global( 39)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9268 58 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9721 58 Inquiry
Wuhan Topule +86-02787215551 +86-19945035818 China 8206 58 Inquiry
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 China 3058 58 Inquiry
Wuhan Augda Biotechnology Co., Ltd 15071299552 China 6687 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Supplier Advantage
Nantong HI-FUTURE Biology Co., Ltd. 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58
Nantong Hanfang Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 58
Wuhan Topule 58
Nantong Hi-Future Biotechnology Co., Ltd 58
Wuhan Augda Biotechnology Co., Ltd 58
Cayman Chemical Company 81
Z-L-NVA-CONH-CH2-2-PY CALPAIN INHIBITOR XII (Rac)-Calpain Inhibitor XII Carbamic acid, [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-, phenylmethyl ester (9CI) PLVWMBFPIAQRHK-UHFFFAOYSA-N benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate 181769-57-3 C26H34N4O5