ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >1-N-Boc-4-(Phenylamino)piperidine

1-N-Boc-4-(Phenylamino)piperidine

1-N-Boc-4-(Phenylamino)piperidine Structure
CAS No.
125541-22-2
Chemical Name:
1-N-Boc-4-(Phenylamino)piperidine
Synonyms
tert-butyl 4-anilinopiperidine-1-carboxylate;1-Boc-4-(phenylaMino)piperidine;tert-butyl 4-(phenylaMino)piperidine-1-carboxylate;1-N-Boc-4-(Phenylamino);Aniline piperidine;(Phenylamino)piperidine;4-(Phenylamino)piperidine, N1-BOC protected;2-Methyl-2-propanyl 4-anilino-1-piperidinecarboxylate;4-(phenylamino)-;1-N-Boc-4-(Phenylami
CBNumber:
CB2262675
Molecular Formula:
C16H24N2O2
Molecular Weight:
276.37
MOL File:
125541-22-2.mol
Modify Date:
2024/5/28 14:12:21

1-N-Boc-4-(Phenylamino)piperidine Properties

Melting point 136-137
Boiling point 400.6±38.0 °C(Predicted)
Density 1.107±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: 15mg/mL; DMSO: 25mg/mL; Ethanol: 25mg/mL; Ethanol:PBS (pH 7.2) (1:1): 0.5mg/mL
form A crystalline solid
pka 5.00±0.20(Predicted)
InChI InChI=1S/C16H24N2O2/c1-16(2,3)20-15(19)18-11-9-14(10-12-18)17-13-7-5-4-6-8-13/h4-8,14,17H,9-12H2,1-3H3
InChIKey HTIWISWAPVQGMI-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(NC2=CC=CC=C2)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  22
Hazard Note  Harmful/Irritant
HazardClass  IRRITANT
HS Code  2933399990
NFPA 704
0
2 0

1-N-Boc-4-(Phenylamino)piperidine Chemical Properties,Uses,Production

Description

4-Anilino-1-Boc-piperidine is an analytical reference standard that is structurally similar to known opioids. 4-Anilino-1-Boc-piperidine is a precursor in the synthesis of 4-anilinopiperidine . This product is intended for research and forensic applications.

Chemical Properties

Pale Brown Solid

Uses

Intermediate in the preparation of Fentanyl derivatives.

Application

1-N-Boc-4-(Phenylamino)piperidine is an amino acid derivative widely employed as a reagent in organic synthesis. This compound exhibits remarkable versatility, finding applications in various fields such as peptide and protein synthesis, organic synthesis, and drug development. It possesses strong basic properties, allowing for diverse reactions with acids that lead to the formation of a wide array of products. The extensive use of this compound in organic synthesis is well-documented, particularly in the synthesis of peptides and proteins. By facilitating the coupling of amino acids, it enables the creation of peptides that can be utilized in diverse applications, including the development of pharmaceutical drugs.

1-N-Boc-4-(Phenylamino)piperidine Preparation Products And Raw materials

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TERT-BUTYL 4-ANILINOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE 1-N-BOC-4-(PHENYLAMINO)PIPERIDINE tert-butyl 4-anilinotetrahydro-1(2H)-pyridinecarboxylate (en) N-tert-Butoxycarbonyl-4-anilinopiperidine 1-N-Boc-4-(Phenylamino)piperidine - 97.0% 1-(tert-Butyloxycarbonyl)-4-(phenylaMino)piperidine 4-(PhenylaMino)-1-piperidinecarboxylic Acid 1,1-DiMethylethyl Ester tert-Butyl 4-(phenylamino)piperidine-1-carboxylate, tert-Butyl 4-anilinopiperidine-1-carboxylate 1-Piperidinecarboxylicacid, 4-(phenylaMino)-, 1,1-diMethylethyl ester 4-(Phenylamino)piperidine,N1-BOCprotected95% 1-N-Boc-4-(Pheny 1-N-Boc-4-(Phenylamino)piperidinelamino)piperidine 1-N-Boc-4-(Phenylamino)piperidine Supplier 1-N-Boc-4- aniline piperidine 4-(phenylamino)- High purity 1-N-Boc-4-(Phenylamino)piperidine CAS 125541-22-2 4-Anilino-1-Boc-piperidine 99%1,1-dimethylethyl ester Widely Used 99% 1-N-Boc-4- (Phenylamino) Piperidine Powder CAS 125541-22-2 Pharmaceutical/1-N-Boc-4- (Phenylamino) Piperidine ethyl 3-oxo-2-phenylbutanoate(BMK)(BMK glycidate oil) ethyl 6-bromo-4-[(dimethylamino)methyl] 1-N-Boc-4-(Phenylami 1-N-Boc-4-(Phenylamino)piperidine Basic information Intermediate for Fentanyl derivatives L-Carnitine/ Orlistat/ Rasagiline 1-N-Boc-4-anilinopiperidine C16H24N2O2 tert-Butyl 4-anilinopiperidine-1-carboxylate 1-N-Boc-4-(Phenylamino)piperidine CAS 125541-22-2 -N-Boc-4-(Phenylamino)Piperidine 4-(Phenylamino)piperidine, N1-BOC protected 1-Boc-4-(phenylaMino)piperidine tert-butyl 4-(phenylaMino)piperidine-1-carboxylate 1-N-Boc-4-(Phenylamino) tert-butyl 4-anilinopiperidine-1-carboxylate Aniline piperidine (Phenylamino)piperidine 2-Methyl-2-propanyl 4-anilino-1-piperidinecarboxylate 1 -N-Boc-4-(Phenylamino)piperidin 1-(tert-Butoxycarbonyl)-4-phenylaminopiperidine 125541-22-2 1225541-22-2 125541-22-4 Intermediates inter Aromatics Heterocycles pharmaceutical Intermediate 125541-22-2 Pharm