Diallyl trisulfide
- CAS No.
- 2050-87-5
- Chemical Name:
- Diallyl trisulfide
- Synonyms
- FEMA 3265;Allitridin;ALLYL TRISULFIDE;ALLYLTRISULPHIDE;DIALLYL TRISULFIDE;DIALLYL TRISULPHIDE;3-diallyltrisulfane;Diallyl pertrisulfide;1,3-Diallyltrisulfane;Diallyl Trisulfide (AS)
- CBNumber:
- CB2269270
- Molecular Formula:
- C6H10S3
- Molecular Weight:
- 178.34
- MOL File:
- 2050-87-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:03
| Boiling point | bp6 92°; bp0.0008 66-67° |
|---|---|
| Density | 1.085 |
| FEMA | 3265 | DIALLYL TRISULFIDE |
| refractive index | nD20 1.5896 |
| storage temp. | -20°C |
| solubility | Soluble in acetone, Ethanol(~3 mg/ml), DMSO (~5 mg/ml), and DMF (~10 mg/ml). |
| form | oil |
| color | Colorless to light yellow |
| Odor | at 0.10 % in propylene glycol. garlic green onion metallic |
| Odor Type | sulfurous |
| Water Solubility | insoluble in water. |
| JECFA Number | 587 |
| InChI | InChI=1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2 |
| InChIKey | UBAXRAHSPKWNCX-UHFFFAOYSA-N |
| SMILES | S(SCC=C)SCC=C |
| LogP | 4.59 |
| CAS DataBase Reference | 2050-87-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Trisulfide, di-2-propenyl(2050-87-5) |
Diallyl trisulfide price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SMB00577 | Diallyl trisulfide ≥97% (HPLC) | 2050-87-5 | 100MG | ₹18759.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SMB00577 | Diallyl trisulfide ≥97% (HPLC) | 2050-87-5 | 500MG | ₹53129.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SMB00289 | Diallyl trisulfide ≥98% (HPLC) | 2050-87-5 | 100MG | ₹15847.8 | 2022-06-14 | Buy |
| ottokemi | D 1342 | Diallyl trisulfide, ≥98% (HPLC) | 2050-87-5 | 100mg | ₹39906 | 2022-05-26 | Buy |
Diallyl trisulfide Chemical Properties,Uses,Production
Description
Hydrogen sulfide (H2S) is an endogenously-produced gaseous second messenger that can regulate many physiological processes. Diallyl trisulfide (DATS) is an organic polysulfide compound found in garlic that acts as an H2S donor. It reduces the survival of prostate cancer PC-3 cells (IC50 = 22 μM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 μM). DATS suppresses the growth of PC-3 xenografts in vivo in mice and induces vascular smooth muscle relaxation. Garlic extracts also lower cholesterol and there is evidence that DATS can alter the expression of genes and inhibit enzymes that are relevant to cholesterol synthesis.
Chemical Properties
Diallyl trisulfide is a yellow liquid with a disagreeable odor. It is a stable transformation product of allicin. Insoluble in water and ethanol, miscible in ether. Natural products are found in onions, garlic, etc. Diallyl trisulfide (DATS) and diallyl disulfide (DADS) are the two major organosulfides in garlic oil.
Occurrence
Reported found in garlic oil.
Uses
Diallyl Trisulfide, is an organosulfur garlic compound that induces neovasculogenesis and has preventive effects against ischemic injuries. Antiarrythmic effect.
Preparation
In nature, diallyl trisulfide is formed from alliin and allicin.
Definition
ChEBI: Diallyl trisulfide is an organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity It has a role as an apoptosis inducer, an estrogen receptor antagonist, an antineoplastic agent, a vasodilator agent, an antioxidant, an anti-inflammatory agent, an insecticide, an antiprotozoal drug, a platelet aggregation inhibitor and an antilipemic drug.
General Description
Diallyl trisulfide (DATS) is one of the organosulfur compounds found in garlic (Allium sativum), and other Allium genera such as onions. This sulfur-rich compound is produced by the rapid disintegration of its metabolic precursor Allicin.
Biochem/physiol Actions
DATS is a potent anti-cancer and chemopreventive agent that regulates apoptosis, metastasis, cell cycle, and angiogenesis in cancer pathways. It is also an excellent neuroprotective agent. DATS elicits antioxidant and anti-inflammatory activities against doxorubicin (DOX)-induced rats brains. It may improve glycemic control, muscle glucose utilization, and insulin secretion in streptozotocin-induced diabetic rats.
Diallyl trisulfide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 6011 | 58 | Inquiry |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | China | 3002 | 58 | Inquiry |
| Hebei Ganmiao New material Technology Co., LTD | +86-17332992504 +86-17332992504 | China | 299 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16220 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
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