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WUWEIZISU C

WUWEIZISU C Structure
CAS No.
61301-33-5
Chemical Name:
WUWEIZISU C
Synonyms
WUWEIZISU C;,8-dimethyl-;SCHIZANDRIN C;(S)-(-)-Schisandrin C;WUWEIZISU C USP/EP/BP;Schisandrin C >=98% (HPLC);Schisandrin C (Schizandrin-C;Schisandrin C (S)-(-)-Schisandrin C;13,14-dimethoxy-6,7-dimethyl-5,6,7,8-tetrahydro[1,3]benzodio...;cycloocta(1,2-f:3,4-f’)bis(1,3)benzodioxole6,7,8,9-tetrahydro-1,13-dimethoxy-7
CBNumber:
CB2327435
Molecular Formula:
C22H24O6
Molecular Weight:
384.42
MOL File:
61301-33-5.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:58
Request For Quotation

WUWEIZISU C Properties

Melting point 122-123℃
Boiling point 549.2±50.0 °C(Predicted)
Density 1.232
solubility DMSO : 8.33 mg/mL (21.67 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form powder
color White
LogP 5.623 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H410
Precautionary statements  P264-P270-P301+P312-P330-P501-P273-P391-P501
NFPA 704
0
2 0

WUWEIZISU C Chemical Properties,Uses,Production

Description

Schisandrin C is a lignan originally isolated from Schizandrae that has diverse biological activities. It decreases viability of U937 cells in a concentration-dependent manner and induces cell cycle arrest at the G1 phase when used at a concentration of 100 μM. Schisandrin C (5-20 μM) decreases hydrogen peroxide-induced cell death and production of reactive oxygen species (ROS) in C2C12 skeletal muscle cells. It also decreases levels of matrix metalloproteinase-2 (MMP-2), MMP-9, COX-2, VCAM-1, IL-1β, and TNF-α in hydrogen peroxide-stimulated C2C12 cells. Schisandrin C decreases lipoteichoic acid-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; ), TNF-α, IL-1β, and IL-6 in mouse primary microglia. In vivo, schisandrin C (200 mg/kg) decreases serum alanine amino transferase (ALT) and aspartate amino transferase (AST) activity, increases hepatic mitochondrial and total glutathione (GSH) levels, and reduces liver injury in a mouse model of acetaminophen-induced liver injury partially via inhibition of the cytochrome P450 (CYP) isoforms CYP2E1, CYP1A2, and CYP3A11.

Uses

Schisandrin C potently inhibits proprotein convertase subtillsin-kexin type 9 (PCSK9) mRNA expression. Also, it displays strong protective effects in SH-SY5Y cells against serum and glucose deprivation (SGD) injury.

WUWEIZISU C Preparation Products And Raw materials

Raw materials

Preparation Products

WUWEIZISU C Suppliers

Global( 181)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3424 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 12210 58 Inquiry
Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23556 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26216 58 Inquiry
Supplier Advantage
career henan chemical co 58
Chengdu GLP biotechnology Co Ltd 58
Chengdu Biopurify Phytochemicals Ltd. 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
Neostar United (Changzhou) Industrial Co., Ltd. 58
Hubei Ipure Biology Co., Ltd 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
ANHUI WITOP BIOTECH CO., LTD 58
Dideu Industries Group Limited 58

61301-33-5(WUWEIZISU C)Related Search:

WUWEIZISU B,WUWEIZISU B 98.0% BY HPLC Schisandrin schisanhenol WUWEIZISU A Schisantherin A
(5S)-6α,7β-Dimethyl-1,2,3,11,12-pentamethoxy(5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene)-5α,6β,10-triol 5-benzoate Gomisin A 2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)- Arisantetralone C 3,5,6,6-tetraMethyl-4,5,5a,6,7,8-hexahydrocyclopenta[c]pentalen-2(1H)-one
schisantherin D SchisandraeChinensis polysaccharides Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-1-ol, 5,6,7,8-tetrahydro-2, 3,13-trimethoxy-6,7-dimethyl-, stereoisomer 4,4'-Biphenol 4-HYDROXY-4'-METHOXYBIPHENYL
4,4'-Dimethoxybiphenyl Masoprocol 2,2'-DIMETHOXYBIPHENYL
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SCHIZANDRIN C WUWEIZISU C ,8-dimethyl- cycloocta(1,2-f:3,4-f’)bis(1,3)benzodioxole6,7,8,9-tetrahydro-1,13-dimethoxy-7 (6R,7S,13aS)-5,6,7,8-Tetrahydro-13,14-dimethoxy-6,7-dimethylcycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole (S)-(-)-Schisandrin C Schisandrin C (S)-(-)-Schisandrin C 13,14-dimethoxy-6,7-dimethyl-5,6,7,8-tetrahydro[1,3]benzodio... WUWEIZISU C USP/EP/BP Schisandrin C >=98% (HPLC) Cycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole, 5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-, (6R,7S,13aS)- Schisandrin C (Schizandrin-C 61301-33-5 C22H24O6 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Miscellaneous Natural Products