Gomisin A
![Gomisin A Structure](CAS/GIF/58546-54-6.gif)
- CAS No.
- 58546-54-6
- Chemical Name:
- Gomisin A
- Synonyms
- D01752;TJN-101;GOMISIN A;Besigomsin;BESIGOMISIN;wuweizichunb;SCHIZANDROL B;SCHISANDROL B;wuweizialcoholb;Grifola frondsa
- CBNumber:
- CB8374224
- Molecular Formula:
- C23H28O7
- Molecular Weight:
- 416.47
- MOL File:
- 58546-54-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:38
Melting point | 88.5°C |
---|---|
Boiling point | 454.79°C (rough estimate) |
Density | 1.1772 (rough estimate) |
refractive index | 1.5300 (estimate) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | DMSO : 50 mg/mL (120.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
form | powder to crystal |
pka | 14.58±0.40(Predicted) |
color | White to Light yellow |
LogP | 4.770 (est) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P501-P270-P264-P301+P312+P330 | |||||||||
Safety Statements | 24/25 | |||||||||
HS Code | 29329990 | |||||||||
NFPA 704 |
|
Gomisin A price More Price(2)
Gomisin A Chemical Properties,Uses,Production
Description
Schisandrol B is a lignan originally isolated from S. chinensis that has hepatoprotective activity. It increases the expression of pregnane X receptor (PXR) target genes involved in bile acid metabolism, including Cyp3a11, Ugt1a1, Oatp2, and Mrp3 in mouse liver and CYP3A4, UGT1A1, and OATP2 in HEK293T cells. It also protects against lithocholic acid-induced hepatic necrosis and intrahepatic cholestasis in wild-type, but not Pxr-null, mice and decreases mortality in a mouse model of cholestasis when administered at a dose of 100 mg/kg twice per day. It also promotes liver regeneration following partial hepatectomy and protects against hepatotoxicity induced by acetaminophen .
Chemical Properties
White powder
Uses
Schizandrol B exhibits potent protective effects of on ET-1-induced dysfunctional human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs). Anti-cholestasis effect.
Gomisin A Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 18646 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3777 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34571 | 58 | Inquiry |
Apeloa Pharmaceutical Co., Ltd. | +86-0571-87635730 +8615858229168 | China | 1478 | 58 | Inquiry |
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