Gomisin A
- ₹4800 - ₹14800
- Product name: Gomisin A
- CAS: 58546-54-6
- MF: C23H28O7
- MW: 416.47
- EINECS:
- MDL Number:MFCD01941645
- Synonyms:2,3,13-tetramethoxy-l-stereoisomer ;benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-6-ol,5,6,7,8-tetrahydro-6,7-dimethy ;wuweizialcoholb ;wuweizichunb ;BESIGOMISIN;GOMISIN A;SCHISANDROL B;SCHIZANDROL B
2 prices
Selected condition:
Brand
- TCI Chemicals (India)
Package
- 5MG
- 25MG
- ManufacturerTCI Chemicals (India)
- Product numberG0537
- Product descriptionGomisin A
- Packaging5MG
- Price₹4800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberG0537
- Product descriptionGomisin A
- Packaging25MG
- Price₹14800
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | G0537 | Gomisin A | 5MG | ₹4800 | 2022-05-26 | Buy |
TCI Chemicals (India) | G0537 | Gomisin A | 25MG | ₹14800 | 2022-05-26 | Buy |
Properties
Melting point :88.5°C
Boiling point :454.79°C (rough estimate)
Density :1.1772 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO : 50 mg/mL (120.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :powder to crystal
pka :14.58±0.40(Predicted)
color :White to Light yellow
LogP :4.770 (est)
Boiling point :454.79°C (rough estimate)
Density :1.1772 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO : 50 mg/mL (120.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :powder to crystal
pka :14.58±0.40(Predicted)
color :White to Light yellow
LogP :4.770 (est)
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
Schisandrol B is a lignan originally isolated from S. chinensis that has hepatoprotective activity. It increases the expression of pregnane X receptor (PXR) target genes involved in bile acid metabolism, including Cyp3a11, Ugt1a1, Oatp2, and Mrp3 in mouse liver and CYP3A4, UGT1A1, and OATP2 in HEK293T cells. It also protects against lithocholic acid-induced hepatic necrosis and intrahepatic cholestasis in wild-type, but not Pxr-null, mice and decreases mortality in a mouse model of cholestasis when administered at a dose of 100 mg/kg twice per day. It also promotes liver regeneration following partial hepatectomy and protects against hepatotoxicity induced by acetaminophen .Related product price
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