WUWEIZISU C
- ₹0
- Product name: WUWEIZISU C
- CAS: 61301-33-5
- MF: C22H24O6
- MW: 384.42
- EINECS:
- MDL Number:MFCD00272170
- Synonyms:SCHIZANDRIN C;WUWEIZISU C;,8-dimethyl- ;cycloocta(1,2-f:3,4-f’)bis(1,3)benzodioxole6,7,8,9-tetrahydro-1,13-dimethoxy-7 ;(6R,7S,13aS)-5,6,7,8-Tetrahydro-13,14-dimethoxy-6,7-dimethylcycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole;(S)-(-)-Schisandrin C;Schisandrin C (S)-(-)-Schisandrin C;13,14-dimethoxy-6,7-dimethyl-5,6,7,8-tetrahydro[1,3]benzodio...
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Properties
Melting point :122-123℃
Boiling point :549.2±50.0 °C(Predicted)
Density :1.232
solubility :DMSO : 8.33 mg/mL (21.67 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :powder
color :White
LogP :5.623 (est)
Boiling point :549.2±50.0 °C(Predicted)
Density :1.232
solubility :DMSO : 8.33 mg/mL (21.67 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :powder
color :White
LogP :5.623 (est)
Safety Information
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Description
Schisandrin C is a lignan originally isolated from Schizandrae that has diverse biological activities. It decreases viability of U937 cells in a concentration-dependent manner and induces cell cycle arrest at the G1 phase when used at a concentration of 100 μM. Schisandrin C (5-20 μM) decreases hydrogen peroxide-induced cell death and production of reactive oxygen species (ROS) in C2C12 skeletal muscle cells. It also decreases levels of matrix metalloproteinase-2 (MMP-2), MMP-9, COX-2, VCAM-1, IL-1β, and TNF-α in hydrogen peroxide-stimulated C2C12 cells. Schisandrin C decreases lipoteichoic acid-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; ), TNF-α, IL-1β, and IL-6 in mouse primary microglia. In vivo, schisandrin C (200 mg/kg) decreases serum alanine amino transferase (ALT) and aspartate amino transferase (AST) activity, increases hepatic mitochondrial and total glutathione (GSH) levels, and reduces liver injury in a mouse model of acetaminophen-induced liver injury partially via inhibition of the cytochrome P450 (CYP) isoforms CYP2E1, CYP1A2, and CYP3A11.More related product prices
SCHIZANDRIN B schisanhenol Schisandrin Schisantherin A Gomisin A 2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)- 2,2'-DIMETHOXYBIPHENYL 4,4'-Dimethoxybiphenyl 4,4'-BiphenolRelated product price
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Suppliers and manufacturers
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
Neostar United (Changzhou) Industrial Co., Ltd.
Hubei Ipure Biology Co., Ltd
Hefei TNJ Chemical Industry Co.,Ltd.
ANHUI WITOP BIOTECH CO., LTD
Dideu Industries Group Limited